Aryl/Hetero-Aryl Tosylates as Coupling Partners in Metal-Mediated Suzuki and Hiyama Cross-Coupling Reactions in Ionic Liquids: Ligand-Free Facile Synthesis of Biaryls/Heterobiaryls

被引：1

作者：

Jadhav, Vinod ^{[1
]}

Kurahatti, Sunita ^{[1
]}

Anchi, Athmanand ^{[1
]}

Jamadar, Imamhusen ^{[1
]}

Kalkhambkar, Rajesh G. ^{[1
]}

Sutar, Suraj M. ^{[2
]}

Kurkuri, Mahaveer ^{[3
]}

Refat, Moamen S. ^{[4
]}

Alsuhaibani, Amnah Mohammed ^{[5
]}

机构：

[1] Karnatak Univ, Dept Chem, Karnatak Sci Coll, Dharwad 580001, Karnataka, India

[2] Yashwantrao Chavan Mahavidyalaya, Dept Chem, Halkarni 416552, Maharashtra, India

[3] JAIN Deemed Univ, Ctr Res Funct Mat CRFM, Jain Global Campus, Bengaluru 562112, Karnataka, India

[4] Taif Univ, Coll Sci, Dept Chem, POB 11099, Taif 21944, Saudi Arabia

[5] Princess Nourah Bint Abdulrahman Univ, Coll Sport Sci & Phys Act, Dept Phys Sport Sci, Riyadh 11671, Saudi Arabia

来源：

CHEMISTRYSELECT | 2024年 / 9卷 / 41期

关键词：

Aryl/hetero-aryl tosylates; Biaryls; Catalysis; Cross-coupling reactions; Green chemistry; Ionic liquids; PALLADIUM CATALYST; IMIDAZOLIUM-ILS; EFFICIENT; MIYAURA; ARENESULFONATES; HALIDES; HECK; SYSTEM; SONOGASHIRA; LIBRARIES;

D O I：

10.1002/slct.202403925

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Diverse libraries of biaryls/heterobiaryls were synthesized by aryl/hetero-aryl tosylates as coupling partners in the ligand-free, Ni-catalyzed Suzuki coupling reaction, and Pd-catalyzed Hiyama cross-coupling reaction in ionic liquids (ILs) as green solvent. In this method easily available and economically viable tosylates were coupled with readily available boronic acids and phenyltriethoxysilanes in Suzuki and Hiyama cross-coupling respectively to yield the corresponding biaryls/heterobiaryls. Mild reaction condition(s), easy workup, moderate to excellent yield of the isolated pure products, wide substrate scope, and recycling/reuse of the ILs are the advantages of this method over the other reported methods.

引用

页数：11

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