Impact of serum albumin and prealbumin as well as anthropometric measurements on long-term survival outcomes after allogeneic stem cell transplantation

individuals with chronic hepatitis infections, especially those who have advanced liver injury. Complement regulatory proteins, namely, CD55 and CD59, may directly disrupt the proper functioning of the complement system. Both proteins are found on platelets and, as a result, might be subjected to autoantibody targeting. This work aimed to assess the expression of complement regulatory proteins (CD59 and CD55) on the platelet surface in patients with hepatitis- associated thrombocytopenia. Methods This case-control study was performed on 90 patients aged 4 to 80. The patients were divided into three equal groups. Group I: included 30 chronic hepatitis patients with hepatitis B virus and thrombocytopenia. Group II: included 30 chronic hepatitis C virus patients with thrombocytopenia. Group III: 30 immune thrombocytopenia patients were used as controls. Results Compared with those in group III CD55, CD59, CD61, and CD42 did not substantially differ among group I and group II patients, however, they significantly decreased when group I was compared with group III control subjects, and they significantly differed when group was compared group III control subjects. A statistically significant positive correlation existed between absolute Results We found a statistically significant association between nutritional laboratory parameters as well as anthropometric measurements with late transplant outcomes, including the incidence of chronic graft-versus- host disease, disease relapse, and transplant-related mortality as well as posttransplant QoL. Conclusion Nutritional laboratory biomarkers and anthropometric measurements in long-term survivors postallogeneic stem cell transplantation were low-cost, noninvasive biomarkers for early and late transplant complications, patients' survival, and QoL. Egypt J Haematol2024 49:378-385 (c) 2024 The Egyptian Journal of Haematology