Successful Treatment of Eosinophilic Pustular Folliculitis With Dupilumab in a 9-Year-Old Boy

被引：0

作者：

Tan, Xi ^{[1
]}

Nie, Shu ^{[1
]}

Chen, Bin ^{[1
]}

Wu, Zhouwei ^{[2
]}

机构：

[1] Shanghai Gen Hosp, Dept Dermatol, Shanghai, Peoples R China

[2] Shanghai Jiao Tong Univ, Sch Med, Shanghai Gen Hosp, Dept Dermatol, Shanghai, Peoples R China

来源：

PEDIATRIC DERMATOLOGY | 2025年

关键词：

child; dupilumab; eosinophilic pustular folliculitis;

D O I：

10.1111/pde.15908

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A 9-year-old boy with eosinophilic pustular folliculitis (EPF) was successfully treated with dupilumab. While reported in adult EPF, this is the first case of EPF treated with dupilumab in a child. Our case suggests dupilumab might be a favorable therapeutic option for EPF in children. Further research is needed to fully elucidate the efficacy and safety of dupilumab in children with EPF and to identify predictive factors for treatment response.

引用

页数：3

共 5 条

[1] Two cases of eosinophilic pustular folliculitis successfully treated with abrocitinib [J].

Cai, Liting ;

Yan, Yunling ;

Li, Yang ;

Lin, Junjie ;

She, Xinyan ;

Wang, Xiaohua .

JOURNAL OF DERMATOLOGY, 2024, 51 (12) :1694-1697

[2] Mepolizumab therapy for eosinophilic pustular folliculitis (Ofuji disease) [J].

Chersi, Filippo ;

Zelin, Enrico ;

Mazzoletti, Vanessa ;

Caposiena, Dante Raffaele Caro ;

Hasa, Zyber ;

Nan, Katiuscia ;

Signoretto, Diego ;

Zalaudek, Iris ;

di Meo, Nicola .

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2024, 38 (11) :e993-e996

[3] Possible interaction between eosinophils and other immune cells in the pathomechanism of eosinophilic pustular folliculitis [J].

Ichimura, Ryuzo ;

Kamiya, Koji ;

Komine, Mayumi ;

Jin, Meijuan ;

Miyauchi, Hitomi ;

Maekawa, Takeo ;

Sakaguchi, Mio ;

Tsuji, Kentaro ;

Kawata, Hirotoshi ;

Ohtsuki, Mamitaro .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 2022, 61 (12) :E499-E501

[4] Treatment of eosinophilic pustular folliculitis with ciclosporin: suppression of mRNA expression of IL-4 and IL-13 [J].

Otsuka, A. ;

Doi, H. ;

Miyachi, Y. ;

Kabashima, K. .

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2010, 24 (12) :1489-1491

[5] Successful Treatment of Eosinophilic Pustular Folliculitis With Dupilumab [J].

Ottavi, Marie ;

Velin, Marine ;

Cardot Leccia, Nathalie ;

Passeron, Thierry .

JAMA DERMATOLOGY, 2024, 160 (01) :114-115

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