Hypopituitarism due to CNS Aspergillus Infection

被引:0
作者
Funakoshi, Shogo [1 ]
Nishiyama, Mitsuru [1 ]
Komori, Masahiro [2 ]
Hyodo, Masamitsu [2 ]
Kawanishi, Yu [3 ]
Ueba, Tetsuya [3 ]
Fujimoto, Shimpei [1 ]
Terada, Yoshio [1 ]
机构
[1] Kochi Univ, Kochi Med Sch, Dept Endocrinol Metab & Nephrol, Kochi, Japan
[2] Kochi Univ, Kochi Med Sch, Dept Otolaryngol Head & Neck Surg, Kochi, Japan
[3] Kochi Univ, Kochi Med Sch, Dept Neurosurg, Kochi, Japan
关键词
hypopituitarism; Aspergillus; hyponatremia; invasive sinus fungal infection; carotid occlusion; PITUITARY ABSCESS; SELLAR ABSCESS; VORICONAZOLE; EXPERIENCE; DIAGNOSIS; PATIENT;
D O I
10.2169/internalmedicine.3390-23
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 59-year-old man was admitted to our hospital with hyponatremia. An endocrine examination indicated panhypopituitarism, and magnetic resonance imaging revealed a mass-like lesion in the pituitary gland. Sinus endoscopy revealed a fungal mass in the sphenoid sinus, and the patient was diagnosed with hypopituitarism due to aspergillosis of the central nervous system (CNS). The patient's hyponatremia resolved with hydrocortisone replacement. Although the right internal carotid artery was eventually occluded, antifungal medications were administered for the aspergillosis, and the patient's general condition improved. The patient's CNS lesions have remained under control since discharge. This is the first case to suggest that ACTH secretion may be relatively preserved in Aspergillus-induced hypopituitarism.
引用
收藏
页码:2953 / 2959
页数:7
相关论文
共 26 条
[1]   Case Report of a Primary Pituitary Abscess and Systematic Literature Review of Pituitary Abscess with a Focus on Patient Outcomes [J].
Agyei, Justice O. ;
Lipinski, Lindsay J. ;
Leonardo, Jody .
WORLD NEUROSURGERY, 2017, 101 :76-92
[2]   An unusual case of a pituitary fossa aspergilloma in an immunocompetent patient mimicking infiltrative tumour [J].
Ahmadzai, Hasib ;
Raley, Darryl Alan ;
Masters, Lynette ;
Davies, Mark .
JOURNAL OF SURGICAL CASE REPORTS, 2013, (04)
[3]   Fungal Mycotic Aneurysm of the Internal Carotid Artery Associated with Sphenoid Sinusitis in an Immunocompromised Patient: A Case Report and Review of the Literature [J].
Azar, Marwan M. ;
Assi, Roland ;
Patel, Natalie ;
Malinis, Maricar F. .
MYCOPATHOLOGIA, 2016, 181 (5-6) :425-433
[4]   Cavernous sinus thrombosis secondary to aspergillus granuloma: A case report and review of the literature [J].
Brenet, Esteban ;
Boulagnon-Rombi, Camille ;
N'guyen, Yohan ;
Litre, Claude-Fabien .
AURIS NASUS LARYNX, 2016, 43 (05) :566-569
[5]   Lung aspergilloma with pituitary invasive aspergillosis presenting as headache and hyponatraemia [J].
Choi, Eunho ;
Kim, Sun Bean ;
Kim, Jong Hun ;
Yoon, Young Kyung .
BMJ CASE REPORTS, 2021, 14 (01)
[6]  
Fujimoto Takashi, 2021, NMC Case Rep J, V8, P343, DOI [10.2176/nmccrj.cr.2020-0189, 10.2176/nmccrj.cr.2020-0189]
[7]   Pituitary abscess: clinical manifestations, diagnosis and treatment of 66 cases from a large pituitary center over 23 years [J].
Gao, Lu ;
Guo, Xiaopeng ;
Tian, Rui ;
Wang, Qiang ;
Feng, Ming ;
Bao, Xinjie ;
Deng, Kan ;
Yao, Yong ;
Lian, Wei ;
Wang, Renzhi ;
Xing, Bing .
PITUITARY, 2017, 20 (02) :189-194
[8]   Hypophysitis: An update on the novel forms, diagnosis and management of disorders of pituitary inflammation [J].
Gubbi, Sriram ;
Hannah-Shmouni, Fady ;
Verbalis, Joseph G. ;
Koch, Christian A. .
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2019, 33 (06)
[9]  
Guy Ali, 2021, Radiol Case Rep, V16, P789, DOI 10.1016/j.radcr.2021.01.030
[10]   Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis [J].
Herbrecht, R ;
Denning, DW ;
Patterson, TF ;
Bennett, JE ;
Greene, RE ;
Oestmann, JW ;
Kern, WV ;
Marr, KA ;
Ribaud, P ;
Lortholary, O ;
Sylvester, R ;
Rubin, RH ;
Wingard, JR ;
Stark, P ;
Durand, C ;
Caillot, D ;
Thiel, E ;
Chandrasekar, PH ;
Hodges, MR ;
Schlamm, HT ;
Troke, PF ;
de Pauw, B .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (06) :408-415