68Ga-FAPI PET/CT Depicted the Fibrosis of Ischemic Colitis

被引：1
作者：
Zheng, Jieling [1 ,2 ]
Ru, Qian [3 ]
Yang, Yun [1 ,2 ]
Miao, Weibing [1 ,2 ,4 ]
机构：
[1] Fujian Med Univ, Affiliated Hosp 1, Dept Nucl Med, 20 Chazhong Rd, Fuzhou 350005, Fujian, Peoples R China
[2] Fujian Med Univ, Affiliated Hosp 1, Natl Reg Med Ctr, Dept Nucl Med, Binhai Campus, Fuzhou, Peoples R China
[3] Fujian Med Univ, Affiliated Hosp 1, Dept Pathol, Fuzhou, Peoples R China
[4] Fujian Med Univ, Affiliated Hosp 1, Fujian Key Lab Precis Med Canc, Fuzhou, Fujian, Peoples R China
来源：
CLINICAL NUCLEAR MEDICINE | 2024年 / 49卷 / 11期
关键词：
Ga-68-FAPI; F-18-FDG; ischemic colitis; PET/CT;
D O I：
10.1097/RLU.0000000000005430
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Ischemic colitis is the most common form of ischemic bowel disease; identification of ischemic colitis with PET/CT is rare. We present a case of unexplained ischemic colitis in a 66-year-old man who underwent F-18-FDG PET/CT to exclude intestinal malignancy and was subsequently recruited in a clinical trial regarding Ga-68-FAPI. 18F-FDG PET/CT showed intense activity in the intestinal lumen where mucosa had chronic inflammation. Conversely, Ga-68-FAPI PET/CT revealed high tracer uptake in the intestinal wall and adjacent mesentery. Our case showed the different distribution pattern of 18F-FDG and Ga-68-FAPI in ischemic colitis.
引用
收藏
页码：1050 / 1052
页数：3
相关论文
共 8 条
[1]   Ischemic bowel disease in 2021 [J].
Ahmed, Monjur .
WORLD JOURNAL OF GASTROENTEROLOGY, 2021, 27 (29) :4746-4762
[2]  
Brandt LJ, 2015, AM J GASTROENTEROL, V110, P18, DOI [10.1038/ajg.2014.395, 10.1038/ajg.2014.295]
[3]   [68Ga]Ga-FAPI-04 PET/CT on assessing Crohn's disease intestinal lesions [J].
Chen, Liming ;
Zhong, Xiaolin ;
Li, Limin ;
Li, Xue ;
Liu, Ya ;
Guo, Chunmei ;
Chen, Yue ;
Huang, Zhanwen .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 50 (05) :1360-1370
[4]   Evaluation of Intestinal Fibrosis with 68Ga-FAPI PET/MR Enterography in Crohn Disease [J].
Scharitzer, Martina ;
Macher-Beer, Andrea ;
Mang, Thomas ;
Unger, Lukas W. ;
Haug, Alexander ;
Reinisch, Walter ;
Weber, Michael ;
Nakuz, Thomas ;
Nics, Lukas ;
Hacker, Marcus ;
Bergmann, Michael ;
Rasul, Sazan .
RADIOLOGY, 2023, 307 (03)
[5]   Renal Interstitial Fibrosis Detected on 18F-AlF-NOTA-FAPI-04 PET/CT in a Patient With Multiple Myeloma [J].
Wang, Hao ;
Deng, Yujiao ;
He, Limeng ;
Deng, Yan ;
Zhang, Wei .
CLINICAL NUCLEAR MEDICINE, 2023, 48 (10) :896-898
[6]   68Ga-FAPI-04 PET/CT in Assessment of Fibroblast Activation in Keloids: A Prospective Pilot Study [J].
Wang, Jiarou ;
Yu, Nanze ;
Wang, Guochang ;
Wang, Rongxi ;
Li, Linlin ;
Jiang, Yuanyuan ;
Sui, Huimin ;
Sun, Yixin ;
Li, Zhijin ;
Long, Xiao ;
Zhu, Zhaohui .
CLINICAL NUCLEAR MEDICINE, 2024, 49 (01) :16-22
[7]   68Ga-FAPI and 18F-PET/CT Images in Intestinal Tuberculosis [J].
Zheng, Jieling ;
Lin, Kaixian ;
Zheng, Shan ;
Yao, Shaobo ;
Miao, Weibing .
CLINICAL NUCLEAR MEDICINE, 2022, 47 (03) :239-240
[8]   Characterization of the benign lesions with increased 68Ga-FAPI-04 uptake in PET/CT [J].
Zheng, Shan ;
Lin, Rong ;
Chen, Shaoming ;
Zheng, Jieling ;
Lin, Zefang ;
Zhang, Ying ;
Xue, Qianqian ;
Chen, Yun ;
Zhang, Jiaying ;
Lin, Kaixian ;
You, Xin ;
Yao, Shaobo ;
Miao, Weibing .
ANNALS OF NUCLEAR MEDICINE, 2021, 35 (12) :1312-1320
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