Roginolisib (IOA-244), a first oral allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3Kδ) in patients with metastatic uveal melanoma

被引:0
作者
Di Giacomo, A. M. [1 ]
Simonelli, M. [2 ]
Santangelo, F. [3 ]
Amato, G. [1 ]
Simonetti, E. [4 ]
Graham, J. [5 ]
Lahn, M. [6 ]
Di Conza, G. [7 ]
Hammett, T. [8 ]
Zorrilla, R. [8 ]
Kaur, P. [9 ]
Ziyang, T. [10 ]
Lakshmikanth, T. [10 ]
Brodin, P. [10 ]
Occhipinti, M. [11 ]
Carlo-Stella, C. [12 ]
Santoro, A. [13 ]
Spiliopoulou, P. [14 ]
Evans, T. R. J. [15 ]
Maio, M. [16 ,17 ]
机构
[1] AOU Senese Santa Maria Scotte, Med Oncol & Immunotherapy, Siena, Italy
[2] IRCCS Humanitas Res Hosp, Med Oncol, Rozzano, Italy
[3] AOU Senese Santa Maria Scotte, Dipartimento Immunoterapia Oncol, Siena, Italy
[4] Azienda Osped Univ Senese, Ist Toscano Tumori, Med Oncol & Immunotherapy, Siena, Italy
[5] BWSCC Beatson West Scotland Canc Ctr, Dept Oncol, Glasgow, Lanark, Scotland
[6] iOnctura SA, Oncol Dept, Oberursel, Switzerland
[7] iOnctura SA, R&D Dept, Geneva, Switzerland
[8] iOnctura SA, Clin Dev, Geneva, Switzerland
[9] iOnctura SA, Clin Dept, Geneva, Switzerland
[10] Karolinska Inst, Womens & Childrens Hlth, Stockholm, Sweden
[11] Radiomics SA, R&D Dept, Liege, Belgium
[12] Humanitas Univ, Dept Hematol & Oncol, Milan, Italy
[13] IRCCS Humanitas Res Hosp, Ctr Canc, Humanitas Canc Ctr, Milan, Italy
[14] BWSCC Beatson West Scotland Canc Ctr, Med Oncol Dept, Glasgow, Lanark, Scotland
[15] Univ Glasgow, Inst Canc Sci, Glasgow, Lanark, Scotland
[16] AOU Senese Santa Maria Scotte, Ctr Immunooncol, Siena, Italy
[17] AOU Senese Santa Maria Scotte, Med Oncol & Immunotherapy Unit, Siena, Italy
关键词
D O I
10.1016/j.annonc.2024.08.693
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
626P
引用
收藏
页码:S500 / S500
页数:1
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