Health-related quality of life of trans people using a specialized health service in Manaus, Amazonas state, Brazil, 2023: a cross-sectional study

Objective: To assess health-related quality of life and associated factors among trans people. Methods: This was a cross-sectional study conducted in 2023. The 12-Item Short- Form Health Survey was used with trans women, trans men, travestis, and non-binary people who were users of a health service in Manaus, capital city ofAmazonas state. Results:Atotal of 71 participants were included: 36 trans women; 29 trans men; 2 travestis; and 4 non-binary people, with a mean age 30.1 years. The physical component scored 44.6 +/- 7.8, and the mental component scored 38.4 +/- 11.1. The emotional aspect with a score of 16.0 +/- 1.1, was the most affected domain. Paid employment was associated with better mental quality of life, while having lived in street situations was associated with worse physical quality of life, with mean differences of 4.4 (95%CI 2.3;6.9) and-3.3 (95%CI-7.7;-2.3) respectively. Conclusion: Among trans people, the mental component was more affected than the physical, with the greatest impairment observed in the emotional aspect. Socioeconomic characteristics were associated with quality of life.