Invasive Aspergillosis in the Intensive Care Unit

被引：0

作者：

Zubovskaia, Anna ^{[1
]}

Vazquez, Jose A. ^{[1
]}

机构：

[1] Augusta Univ, Med Coll Georgia, Div Infect Dis, Augusta, GA 30912 USA

来源：

JOURNAL OF FUNGI | 2025年 / 11卷 / 01期

关键词：

aspergillosis; intensive care unit; invasive aspergillosis; antifungals; COMBINATION ANTIFUNGAL THERAPY; PULMONARY ASPERGILLOSIS; GALACTOMANNAN ANTIGENEMIA; TRANSPLANT RECIPIENTS; FUNGAL-INFECTIONS; MOLD DISEASE; DIAGNOSIS; RESISTANT; FUMIGATUS; EPIDEMIOLOGY;

D O I：

10.3390/jof11010070

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Invasive aspergillosis (IA) is a fungal infection, which has traditionally been associated with neutropenia and immunosuppressive therapies. Our understanding of invasive aspergillosis has been evolving and, in the past few decades, IA among ICU patients has been recognized as a common infection and has become more widely recognized. The diagnosis and management of invasive aspergillosis in the ICU is particularly challenging, due to the unstable clinical condition of the patients, lack of diagnostic markers, increased risk of further clinical deterioration, multiple comorbidities, and a need for early assessment and treatment. In this article, we will discuss the challenges and pitfalls of the diagnosis and management of invasive aspergillosis in an ICU setting, along with a review of the current literature that is pertinent and specific to this population.

引用

页数：22

共 126 条

[51] Invasive pulmonary aspergillosis: frequency and meaning of the "hypodense sign" on unenhanced CT [J].

Horger, M ;

Einsele, H ;

Schumacher, U ;

Wehrmann, M ;

Hebart, H ;

Lengerke, C ;

Vonthein, R ;

Claussen, CD ;

Pfannenberg, C .

BRITISH JOURNAL OF RADIOLOGY, 2005, 78 (932) :697-703

[52] Diagnostic contribution of positron emission tomography with [18F]fluorodeoxyglucose for invasive fungal infections [J].

Hot, A. ;

Maunoury, C. ;

Poiree, S. ;

Lanternier, F. ;

Viard, J. P. ;

Loulergue, P. ;

Coignard, H. ;

Bougnoux, M. E. ;

Suarez, F. ;

Rubio, M. T. ;

Mahlaoui, N. ;

Dupont, B. ;

Lecuit, M. ;

Faraggi, M. ;

Lortholary, O. .

CLINICAL MICROBIOLOGY AND INFECTION, 2011, 17 (03) :409-417

[53] Comparison of a novel lateral-flow device to galactomannan assay at different time periods for detections of invasive aspergillosis [J].

Hsiao, Hui-Hua ;

Liu, Yi-Chang ;

Wang, Hui -Ching ;

Du, Jeng-Shiun ;

Tang, Shih-Hao ;

Yeh, Tsung-Jang ;

Hsieh, Chieh-Yu ;

Gau, Yuh-Ching ;

Ke, Ya-Lun ;

Chuang, Tzer-Ming ;

Hsiao, Chi -En ;

Yen, Chia -Hung ;

Cho, Shih-Feng ;

Hsiao, Samuel Yien ;

Chiou, Shyh-Shin ;

Lin, Shang-Yi ;

Hsu, Chin -Mu ;

Lu, Po-Liang .

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 2022, 121 (10) :2123-2129

[54] Invasive pulmonary aspergillosis in patients with influenza infection: A retrospective study and review of the literature [J].

Huang, Linna ;

Zhang, Nannan ;

Huang, Xu ;

Xiong, Shuyu ;

Feng, Yingying ;

Zhang, Yi ;

Li, Min ;

Zhan, Qingyuan .

CLINICAL RESPIRATORY JOURNAL, 2019, 13 (04) :202-211

[55] COVID-19-associated pulmonary aspergillosis in mechanically ventilated patients: a prospective, multicentre UK study [J].

Hurt, William ;

Youngs, Jonathan ;

Ball, Jonathan ;

Edgeworth, Jonathan ;

Hopkins, Philip ;

Jenkins, David R. ;

Leaver, Susannah ;

Mazzella, Andrea ;

Molloy, Sile F. ;

Schelenz, Silke ;

Wise, Matt P. ;

White, P. Lewis ;

Yusuff, Hakeem ;

Wyncoll, Duncan ;

Bicanic, Tihana .

THORAX, 2024, 79 (01) :75-82

[56] Diagnostic Value of Microbial Cell-free DNA Sequencing for Suspected Invasive Fungal Infections: A Retrospective Multicenter Cohort Study [J].

Huygens, Sammy ;

Schauwvlieghe, Alexander ;

Wlazlo, Nick ;

Moors, Ine ;

Boelens, Jerina ;

Reynders, Marijke ;

Chong, Ga-Lai ;

Klaassen, Corne H. W. ;

Rijnders, Bart J. A. .

OPEN FORUM INFECTIOUS DISEASES, 2024, 11 (06)

[57] Risk factors for COVID-19 associated pulmonary aspergillosis and outcomes in patients with acute respiratory failure in a respiratory sub-intensive care unit [J].

Iacovelli, Alessandra ;

Oliva, Alessandra ;

Mirabelli, Flavio Marco ;

Giannone, Silvia ;

Laguardia, Marianna ;

Morviducci, Matteo ;

Nicolardi, Maria Luisa ;

Repaci, Emma ;

Sanzari, Maria Teresa ;

Leanza, Cristiana ;

Raponi, Giammarco ;

Mastroianni, Claudio ;

Palange, Paolo .

BMC INFECTIOUS DISEASES, 2024, 24 (01)

[58] Aspergillus PCR in Bronchoalveolar Lavage Fluid for the Diagnosis and Prognosis of Aspergillosis in Patients With Hematological and Non-hematological Conditions [J].

Imbert, Sebastien ;

Meyer, Isabelle ;

Palous, Martine ;

Brossas, Jean-Yves ;

Uzunov, Madalina ;

Touafek, Feriel ;

Gay, Frederick ;

Trosini-Desert, Valery ;

Fekkar, Arnaud .

FRONTIERS IN MICROBIOLOGY, 2018, 9

[59] Study protocol: A randomized, double-blind, placebo-controlled trial of isavuconazole prophylaxis for the prevention of covid-19-associated pulmonary aspergillosis [J].

Jenks, Jeffrey D. ;

Hoenigl, Martin ;

Thompson III, George R. .

CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS, 2024, 39

[60] Invasive aspergillosis in critically ill patients: Review of definitions and diagnostic approaches [J].

Jenks, Jeffrey D. ;

Nam, Hannah H. ;

Hoenigl, Martin .

MYCOSES, 2021, 64 (09) :1002-1014

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