Evaluation of Complete Blood Count Parameters in Patients With Diabetes Mellitus: A Systematic Review

被引：0
作者：
Aghaei, Mojtaba [1 ,2 ,3 ]
Bahreiny, Seyed Sobhan [4 ]
Zayeri, Zeynab Deris [5 ]
Davari, Nader [2 ]
Abolhasani, Mohammad Mehdi [3 ]
Saki, Najmaldin [1 ,2 ]
机构：
[1] Ahvaz Jundishapur Univ Med Sci, Sch Allied Med, Dept Med Lab Sci, Ahvaz, Iran
[2] Ahvaz Jundishapur Univ Med Sci, Hlth Res Inst, Thalassemia & Hemoglobinopathy Res Ctr, Ahvaz, Iran
[3] Ahvaz Jundishapur Univ Med Sci, Student Res Comm, Ahvaz, Iran
[4] Univ Tehran Med Sci, Sch Med, Dept Physiol, Tehran, Iran
[5] Ahvaz Jundishapur Univ Med Sci, Golestan Hosp, Clin Res Dev Unit, Ahvaz, Iran
来源：
HEALTH SCIENCE REPORTS | 2025年 / 8卷 / 02期
关键词：
blood cell count; diabetes mellitus; inflammation; leukocytes; mean platelet volume; MEAN PLATELET VOLUME; CELL DISTRIBUTION WIDTH; TO-LYMPHOCYTE RATIO; LONG-TERM MORTALITY; MICROVASCULAR COMPLICATIONS; CARDIOVASCULAR-DISEASE; ELEVATED NEUTROPHIL; CHRONIC INFLAMMATION; GLYCATED HEMOGLOBIN; ARTERIAL STIFFNESS;
D O I：
10.1002/hsr2.70488
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Background and Aims Several studies were performed to evaluate the relationship between CBC and patients with diabetes mellitus (DM). In this review, we discussed the prognostic value of CBC parameters in DM patients. Methods English literature was searched and retrieved from the Google Scholar search engine and PubMed database (1980-2024). "Diabetes mellitus," "Blood cell count," "Mean platelet volume," "Leukocytes," and "Inflammation" were used as keywords. Results DM increases vascular inflammation and oxidative stress, while vascular inflammation affects erythropoiesis and red blood cell deformation, thus increasing red cell distribution width (RDW). Mean platelet volume (MPV) is another useful prognostic biomarker for DM patients. Additionally, elevated neutrophil-lymphocyte ratio (NLR) levels are associated with poor glycemic control in T2DM patients, so it can be used as a screening tool in diabetic follow-up. Conclusion RDW can be used as a valuable independent biomarker to assess the prognosis of patients with DM. MPV can also be used as a noninvasive, widely available, and low-cost marker as a key factor as well as a Prognostic/diagnostic biomarker that could be used for DM patients. Total white blood cell count, NLR, Mean platelet volume lymphocyte ratio (MPVLR), and monocyte to high-density lipoprotein ratio (MHR) are valuable biomarkers in predicting DM.
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页数：12
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