Obesity is a pandemic problem that correlates with a cluster of metabolic factors leading to poor cardiovascular outcomes, morbidity, and an increased risk of overall mortality. It is necessary to approach obesity with a comprehensive treatment plan, which may involve lifestyle modifications (diet, exercise, and behavioral therapy) and pharmacological interventions. This article provides an overview of the mechanisms of action, efficacy, and safety of available long-term anti-obesity drugs and introduces other potential agents under investigation.
机构:
Weill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, New York, NY USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Aronne, Louis J.
Sattar, Naveed
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Univ Glasgow, BHF Glasgow Cardiovasc Res Ctr, Sch Cardiovasc & Metab Hlth, Glasgow, ScotlandWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Sattar, Naveed
Horn, Deborah B.
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Univ Texas Houston, Univ Texas Ctr Obes Med & Metab Performance, McGovern Med Sch, Dept Surg, Houston, TX USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Horn, Deborah B.
Bays, Harold E.
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Louisville Metab & Atherosclerosis Res Ctr, Louisville, KY USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Bays, Harold E.
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Wharton, Sean
Lin, Wen-Yuan
论文数: 0引用数: 0
h-index: 0
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China Med Univ Hosp, Dept Family Med, Taichung, TaiwanWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Lin, Wen-Yuan
Ahmad, Nadia N.
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h-index: 0
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Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Ahmad, Nadia N.
Zhang, Shuyu
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h-index: 0
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Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Zhang, Shuyu
Liao, Ran
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h-index: 0
机构:
Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Liao, Ran
Bunck, Mathijs C.
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Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Bunck, Mathijs C.
Jouravskaya, Irina
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h-index: 0
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Eli Lilly & Co, Moscow, RussiaWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Jouravskaya, Irina
Murphy, Madhumita A.
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Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Murphy, Madhumita A.
[J].
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION,
2024,
331
(01):
: 38
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48
机构:
Univ Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark
Astrup, Arne
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Madsbad, Sten
Breum, Leif
论文数: 0引用数: 0
h-index: 0
机构:
Koge Hosp, Dept Med, Koge, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark
Breum, Leif
Jensen, Thomas J.
论文数: 0引用数: 0
h-index: 0
机构:
Cyncron Clin Res Unit, Copenhagen, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark
Jensen, Thomas J.
Kroustrup, Jens Peter
论文数: 0引用数: 0
h-index: 0
机构:
Aalborg Hosp, Dept Endocrinol, Aalborg, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark
Kroustrup, Jens Peter
Larsen, Thomas Meinert
论文数: 0引用数: 0
h-index: 0
机构:
Univ Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark
机构:
Weill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, New York, NY USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Aronne, Louis J.
Sattar, Naveed
论文数: 0引用数: 0
h-index: 0
机构:
Univ Glasgow, BHF Glasgow Cardiovasc Res Ctr, Sch Cardiovasc & Metab Hlth, Glasgow, ScotlandWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Sattar, Naveed
Horn, Deborah B.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas Houston, Univ Texas Ctr Obes Med & Metab Performance, McGovern Med Sch, Dept Surg, Houston, TX USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Horn, Deborah B.
Bays, Harold E.
论文数: 0引用数: 0
h-index: 0
机构:
Louisville Metab & Atherosclerosis Res Ctr, Louisville, KY USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Bays, Harold E.
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h-index:
机构:
Wharton, Sean
Lin, Wen-Yuan
论文数: 0引用数: 0
h-index: 0
机构:
China Med Univ Hosp, Dept Family Med, Taichung, TaiwanWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Lin, Wen-Yuan
Ahmad, Nadia N.
论文数: 0引用数: 0
h-index: 0
机构:
Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Ahmad, Nadia N.
Zhang, Shuyu
论文数: 0引用数: 0
h-index: 0
机构:
Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Zhang, Shuyu
Liao, Ran
论文数: 0引用数: 0
h-index: 0
机构:
Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Liao, Ran
Bunck, Mathijs C.
论文数: 0引用数: 0
h-index: 0
机构:
Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Bunck, Mathijs C.
Jouravskaya, Irina
论文数: 0引用数: 0
h-index: 0
机构:
Eli Lilly & Co, Moscow, RussiaWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Jouravskaya, Irina
Murphy, Madhumita A.
论文数: 0引用数: 0
h-index: 0
机构:
Eli Lilly & Co, Indianapolis, IN USAWeill Cornell Med, Comprehens Weight Control Ctr, Div Endocrinol Diabet & Metab, 1305 York Ave,Fourth Floor, New York, NY 10065 USA
Murphy, Madhumita A.
[J].
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION,
2024,
331
(01):
: 38
-
48
机构:
Univ Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark
Astrup, Arne
论文数: 引用数:
h-index:
机构:
Madsbad, Sten
Breum, Leif
论文数: 0引用数: 0
h-index: 0
机构:
Koge Hosp, Dept Med, Koge, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark
Breum, Leif
Jensen, Thomas J.
论文数: 0引用数: 0
h-index: 0
机构:
Cyncron Clin Res Unit, Copenhagen, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark
Jensen, Thomas J.
Kroustrup, Jens Peter
论文数: 0引用数: 0
h-index: 0
机构:
Aalborg Hosp, Dept Endocrinol, Aalborg, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark
Kroustrup, Jens Peter
Larsen, Thomas Meinert
论文数: 0引用数: 0
h-index: 0
机构:
Univ Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, DenmarkUniv Copenhagen, Dept Human Nutr, Fac Life Sci, DK-1958 Frederiksberg, Denmark