Carbon ion radiation therapy in prostate cancer: The importance of dosage

被引：0

作者：

Treechairusame, Teeradon ^{[1
]}

Taweesedt, Pahnwat T. ^{[2
,3
]}

机构：

[1] Mahidol Univ, Fac Med, Dept Radiol, Div Radiat Oncol,Siriraj Hosp, Bangkok 10700, Thailand

[2] Stanford Univ, Dept Psychiat & Behav Sci, 401 Quarry Rd, Stanford, CA 94305 USA

[3] VA Palo Alto Hlth Care Syst, Sierra Pacific Mental Illness Res Educ & Clin Ctr, Palo Alto, CA 94304 USA

来源：

WORLD JOURNAL OF RADIOLOGY | 2024年 / 16卷 / 11期

关键词：

Prostate cancer; Carbon ion radiotherapy; Bleeding; Toxicity; Dose; RANDOMIZED-TRIAL; ALPHA/BETA RATIO; RADIOTHERAPY; PARAMETERS; MODEL;

D O I：

10.4329/wjr.v16.i11.696

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

In this article, we comment on the article by Ono et al. We focus specifically on the carbon ion radiotherapy studies and the method to calculate the dosing schedule. While photon hypofractionated radiotherapy in prostate cancer has demonstrated improvement in tumor control with reduced gastrointestinal toxicity compared to conventional radiotherapy, carbon ion radiotherapy (CIRT) offers additional physical and biological advantages. Recent findings, including those from Ono et al, have established new dose constraints of CIRT for prostate cancer treatment and risk factors for rectal bleeding. Due to limited data on CIRT dosing, this study underscores the need for more research to refine dose calculation methods and better understand their effects on clinical outcomes.

引用

页数：5

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