Labor Market Participation and Income in Patients With Inflammatory Bowel Disease Onset Before Young Adulthood-The Role of Disease Severity and Mental Health

Background and Aims: Only few studies have examined the socioeconomic consequences of being diagnosed with inflammatory bowel disease (IBD) in childhood or youth. Disease severity has been linked to lower earnings, but little attention has been paid to comorbid mental health conditions. The aim is to examine labor market participation (LMP) and income in patients with IBD onset in childhood or youth and examine how disease severity and mental health conditions affect LMP. "<br /> Methods: In this register-based cohort study, we included patients with IBD onset before 25 years of age and matched comparators. We estimated the relative risk (RR) of having low LMP and the median yearly income from ages 26 to 30. RR of low LMP was also assessed in subgroups of patients based on disease severity (severe/nonsevere) and mental health conditions (yes/no).<br /> Results: A total of 3398 patients with IBD and 28 207 comparators were included. Overall, patients with IBD more often had low LMP (16.4% vs 14.4% in comparators), but slightly higher income (median yearly income difference at age 30: 1141 Euro [95% CI, 483-1798]). In subgroup analyses, only patients with severe IBD had a higher risk of low LMP (RR: 1.46 [95% CI, 1.23-1.72]), whereas patients with nonsevere IBD did not. Among patients with severe disease and mental health conditions, 46% had low LMP (RR: 5.03 [95% CI, 4.38-5.78]). Conclusions: Patients with IBD more often had low LMP, but their income was not affected. The subgroup of patients with severe disease and mental health conditions had the highest risk of low LMP