Effects of exercise on muscular diseases

被引：0

作者：

Boulinguiez, Alexis ^{[1
]}

Bouragba, Dounia ^{[1
]}

Crisol, Barbara ^{[1
]}

Bigot, Anne ^{[1
]}

Butler-Browne, Gillian ^{[1
]}

Trollet, Capucine ^{[1
]}

机构：

[1] Sorbonne Univ, Inst Myol, Ctr Rech myol, INSERM, Paris, France

来源：

M S-MEDECINE SCIENCES | 2024年 / 40卷

关键词：

SKELETAL-MUSCLE; PHYSICAL-ACTIVITY; STRENGTH; ENDURANCE; EXPRESSION; BENEFITS;

D O I：

10.1051/medsci/2024161

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Les myopathies constituent un groupe heterogene de maladies caracterisees par une faiblesse et une degenerescence progressive des muscles. Alors que ces maladies impactent fortement la qualite de vie des patients, de plus en plus d'etudes precliniques et cliniques suggerent que des exercices physiques adaptes sont benefiques pour attenuer certains symptomes et ameliorer plusieurs parametres fonctionnels. Cette breve revue de la litterature evoque l'avancee actuelle des recherches sur les effets de l'exercice physique chez l'Homme dans diverses maladies musculaires, en explorant son impact sur les mecanismes moleculaires, la force, l'endurance, la fonction musculaire et la qualite de vie. Myopathies are a heterogeneous group of diseases characterized by progressive muscle weakness and degeneration. While muscle diseases have a major impact on patients' quality of life, a growing number of pre-clinical and clinical studies suggest that adapted physical exercise is beneficial in alleviating some symptoms and improving some functional parameters. This brief review of the literature discusses the current state of research about the effects of exercise in humans with various muscle diseases, exploring its impact on molecular mechanisms, muscle strength, endurance, function and the quality of life.

引用

页码：17 / 21

页数：5

共 44 条

[1] Avila G., Disturbed Ca2+ Homeostasis in Muscle-Wasting Disorders, Adv Exp Med Biol, 1088, pp. 307-326, (2018)
[2] Zampieri S., Mammucari C., Romanello V., Et al., Physical exercise in aging human skeletal muscle increases mitochondrial calcium uniporter expression levels and affects mitochondria dynamics, Physiological Reports, 4, (2016)
[3] Prokopchuk O., Liu Y., Wang L., Et al., Skeletal muscle IL-4, IL-4Ralpha, IL-13 and IL-13Ralpha1 expression and response to strength training, Exerc Immunol Rev, 13, pp. 67-75, (2007)
[4] Panagiotakos D.B., Pitsavos C., Chrysohoou C., Et al., The associations between leisure-time physical activity and inflammatory and coagulation markers related to cardiovascular disease: the ATTICA Study, Preventive Medicine, 40, pp. 432-437, (2005)
[5] De Mario A., Gherardi G., Rizzuto R., Et al., Skeletal muscle mitochondria in health and disease, Cell Calcium, 94, (2021)
[6] Freyssenet D., Berthon P., Denis C., Mitochondrial biogenesis in skeletal muscle in response to endurance exercises, Arch Physiol Biochem, 104, pp. 129-141, (1996)
[7] Bouzid M.A., Filaire E., Matran R., Et al., Lifelong Voluntary Exercise Modulates Age-Related Changes in Oxidative Stress, Int J Sports Med, 39, pp. 21-28, (2018)
[8] Daussin F.N., Zoll J., Ponsot E., Et al., Training at high exercise intensity promotes qualitative adaptations of mitochondrial function in human skeletal muscle, J Appl Physiol (1985), 104, pp. 1436-1441, (2008)
[9] Abu-Baker A., Messaed C., Laganiere J., Et al., Involvement of the ubiquitinproteasome pathway and molecular chaperones in oculopharyngeal muscular dystrophy, Hum Mol Genet, 12, pp. 2609-2623, (2003)
[10] Afroze D., Kumar A., ER stress in skeletal muscle remodeling and myopathies, FEBS J, 286, pp. 379-398, (2019)

← 1 2 3 4 5 →