Revitalizing sumatriptan: transforming expired medication into a potent solution for corrosion control in acidic environments

被引：1

作者：

Renuka, P. H. ^{[1
]}

Srilatha, Rao ^{[2
]}

Shree, S. Smitha ^{[2
]}

Arathi, A. ^{[2
]}

Prashanth, G. K. ^{[3
]}

Lalithamba, H. S. ^{[4
]}

Bhagya, N. P. ^{[5
]}

机构：

[1] Visvesvaraya Technol Univ, Belagavi, India

[2] VTU, Nitte Meenakshi Inst Technol, Dept Chem, Bengaluru 560064, Karnataka, India

[3] VTU, Sir M Visvesvaraya Inst Technol, Dept Chem, Bengaluru, Karnataka, India

[4] Siddaganga Inst Technol, Dept Chem, Tumkur, India

[5] VTU, Sai Vidya Inst Technol, Dept Chem, Bengaluru, Karnataka, India

来源：

CORROSION ENGINEERING SCIENCE AND TECHNOLOGY | 2025年 / 60卷 / 05期

关键词：

Expired pharmaceuticals; corrosion inhibitors; electrochemical techniques; langmuir adsorption isotherm; sustainable industrial applications; MILD-STEEL; INHIBITION; DRUG; GREEN; CHLORIDE;

D O I：

10.1177/1478422X241297611

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The concerns regarding pharmaceutical waste, particularly expired drugs have prompted the exploration of their alternative applications. This research highlights the potential of repurposing expired pharmaceuticals as eco-friendly corrosion inhibitors for their industrial applications. An expired drug sumatriptan was investigated for its anticorrosive properties on MS in 1 M HCl medium. Electrochemical techniques, including potentiodynamic polarization and electrochemical impedance spectroscopy, were employed to evaluate the inhibition efficiency and complemented by surface characterization studies (SEM, EDAX, CA and AFM). The results demonstrated that sumatriptan acts as an effective mixed-type inhibitor, achieving maximum inhibition efficiencies of 94.51% and 93.85% from PDP and EIS studies respectively for 500 ppm at 318 K. The adsorption of sumatriptan on the metal surface followed the Langmuir isotherm having an R2 value of similar to 1, suggesting a physical adsorption behaviour with Delta G degrees values ranging from -16.286 to -21.518 kJ mol-1. The results demonstrate the effectiveness of sumatriptan as a corrosion inhibitor and the potential of repurposing expired pharmaceuticals as eco-friendly and sustainable alternatives.

引用

页码：348 / 363

页数：16

共 52 条

[1] Expired Antifungal Drugs as Effective Corrosion Inhibitors for Carbon Steel in 1 M HCl Solution: Practical and Theoretical Approaches [J].