Decompensated Cirrhosis with Hepatopulmonary Syndrome in a Patient with Interrupted Treatment for Hypopituitarism: A Case Report

被引：0

作者：

Tadokoro, Tomoko ^{[1
]}

Tani, Joji ^{[1
]}

Sato, Yudai ^{[1
]}

Yano, Rie ^{[1
]}

Takuma, Kei ^{[1
]}

Nakahara, Mai ^{[1
]}

Oura, Kyoko ^{[1
]}

Fujita, Koji ^{[1
]}

Ono, Masafumi ^{[1
]}

Tobiume, Atsushi ^{[2
]}

Sato, Seisuke ^{[3
]}

Inoue, Takuya ^{[4
]}

Morishita, Asahiro ^{[1
]}

Kobara, Hideki ^{[1
]}

机构：

[1] Kagawa Univ, Fac Med, Dept Gastroenterol & Neurol, Kagawa, Japan

[2] Kagawa Univ, Fac Med, Dept Cardiorenal & Cerebrovas cular Med, Kagawa, Japan

[3] Kagawa Univ, Fac Med, Dept Endocrinol & Metab, Kagawa, Japan

[4] Kagawa Univ, Fac Med, Dept Internal Med, Div Hematol Rheumatol & Resp Med, Kagawa, Japan

来源：

INTERNAL MEDICINE | 2025年

关键词：

liver cirrhosis; growth hormone; adult growth hormone deficiency; panhypopituitarism; craniopharyngioma; hepatopulmonary syndrome; FATTY LIVER-DISEASE; NONALCOHOLIC STEATOHEPATITIS; HORMONE-REPLACEMENT; TRANSPLANTATION; THERAPY;

D O I：

10.2169/internalmedicine.4753-24

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 32-year-old man presented with cirrhosis. At 8 years of age, he underwent resection of a craniopharyngioma, which resulted in panhypopituitarism. He underwent self-interrupted hormone replacement therapy at 20 years of age. Computed tomography revealed severe fatty liver and cirrhosis. An endocrinological evaluation revealed panhypopituitarism. Further assessment revealed a diagnosis of hepatopulmonary syndrome. Home oxygen therapy and hormone replacement therapy were initiated. Despite these efforts, poorly controlled hypothalamic obesity led to liver failure, and the patient is currently awaiting liver transplantation. Liver cirrhosis associated with long-term panhypopituitarism may have a poor prognosis even with hormone replacement therapy.

引用

页数：5

共 21 条

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