Molecular mechanism of 5-FU resistance via regulation of nucleic acid metabolic pathway in human colorectal cancer cells

被引:0
|
作者
Nakayama, Koichiro [1 ]
Sato, Akira [1 ]
机构
[1] Tokyo Univ Sci, Fac Pharm Sci, Dept Biochem, Tokyo, Japan
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P-2339
引用
收藏
页码:1230 / 1230
页数:1
相关论文
共 50 条
  • [41] 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation
    Cho, Yong-Hee
    Ro, Eun Ji
    Yoon, Jeong-Su
    Mizutani, Tomohiro
    Kang, Dong-Woo
    Park, Jong-Chan
    Kim, Tae Il
    Clevers, Hans
    Choi, Kang-Yell
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [42] Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells
    Zhang, Qian
    Liu, Rui-Xian
    Chan, Ka-Wo
    Hu, Jiancong
    Zhang, Jingdan
    Wei, Lili
    Tan, Huiliu
    Yang, Xiangling
    Liu, Huanliang
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 38 (1)
  • [43] Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells
    Qian Zhang
    Rui-Xian Liu
    Ka-Wo Chan
    Jiancong Hu
    Jingdan Zhang
    Lili Wei
    Huiliu Tan
    Xiangling Yang
    Huanliang Liu
    Journal of Experimental & Clinical Cancer Research, 38
  • [44] 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation
    Yong-Hee Cho
    Eun Ji Ro
    Jeong-Su Yoon
    Tomohiro Mizutani
    Dong-Woo Kang
    Jong-Chan Park
    Tae Il Kim
    Hans Clevers
    Kang-Yell Choi
    Nature Communications, 11
  • [45] Down-regulation of cIAP2 enhances 5-FU sensitivity through the apoptotic pathway in human colon cancer cells
    Karasawa, Hideaki
    Miura, Koh
    Fujibuchi, Wataru
    Ishida, Kazuyuki
    Kaneko, Naoyuki
    Kinouchi, Makoto
    Okabe, Mitsunori
    Ando, Toshinori
    Murata, Yukio
    Sasaki, Hiroyuki
    Takami, Kazuhiro
    Yamamura, Akihiro
    Shibata, Chikashi
    Sasaki, Iwao
    CANCER SCIENCE, 2009, 100 (05) : 903 - 913
  • [46] Circ-ERBB2 knockdown sensitized colorectal cancer cells to 5-FU via miR-181a-5p/PTEN/Akt pathway
    Zhang, Yueli
    Wang, Xinchun
    Wang, Shuyun
    Liu, Jia
    Li, Ruijia
    Li, Xiaoxia
    Zhang, Rui
    JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2023, 37 (04)
  • [47] Predicting Agents That Can Overcome 5-FU Resistance in Colorectal Cancers via Pharmacogenomic Analysis
    Huang, Tsui-Chin
    Peng, Kuan-Chieh
    Kuo, Tzu-Ting
    Lin, Li-Chun
    Liu, Bai-Chia
    Ye, Shu-Ping
    Chu, Chien-Chou
    Hsia, Shih-Min
    Chang, Hsin-Yi
    BIOMEDICINES, 2021, 9 (08)
  • [48] TCTP is induced early in colorectal cancer, it is translationally regulated via the Akt/mTORC1 pathway, and it contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin
    Bommer, U. A.
    Vine, K. L.
    Iadevaia, V.
    Belfiore, L.
    Engel, M.
    Puri, P.
    Lochhead, A.
    Chen, J.
    Fildes, K.
    Proud, C. G.
    FEBS JOURNAL, 2015, 282 : 95 - 95
  • [49] DCBLD2 Affects the Development of Colorectal Cancer via EMT and Angiogenesis and Modulates 5-FU Drug Resistance
    Xie, Pan
    Yuan, Fu-Qiang
    Huang, Ma-Sha
    Zhang, Wei
    Zhou, Hong-Hao
    Li, Xi
    Liu, Zhao-Qian
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
  • [50] Clinical Usefulness of 5-FU Metabolic Enzymes as Predictive Markers of Response to Chemotherapy in Colorectal Cancer
    Ion Cristóbal
    Rebeca Manso
    Paula González-Alonso
    Juan Madoz-Gurpide
    Federico Rojo
    Jesús García-Foncillas
    World Journal of Surgery, 2016, 40 : 1017 - 1018