ATAK (Adrenaline, Takotsubo, anaphylaxis, and Kounis hypersensitivity-associated syndrome) following common cobra (Naja naja) bite: A case report from Sri Lanka

被引：1
作者：
Wijesinghe, W. Anura K. [1 ]
Rathnasekara, Thilina [1 ]
Wanniarachchi, Ajith W. [2 ]
Silva, Anjana [3 ]
Siribaddana, Sisira [4 ]
机构：
[1] Univ Colombo, Postgrad Inst Med, Colombo, Sri Lanka
[2] Teaching Hosp Anuradhapura, Anuradhapura, Sri Lanka
[3] Rajarata Univ Sri Lanka, Fac Med & Allied Sci, Dept Parasitol, Mihintale, Sri Lanka
[4] Rajarata Univ Sri Lanka, Fac Med & Allied Sci, Dept Med, Mihintale, Sri Lanka
来源：
TOXICON | 2024年 / 252卷
关键词：
Takotsubo cardiomyopathy; Kounis syndrome; Cobra bite; Naja naja; Non-ST elevated myocardial infarction; Catecholamine surge. ATAK complex; CORONARY SYNDROME; PATHOPHYSIOLOGY;
D O I：
10.1016/j.toxicon.2024.108180
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A 68-year-old woman, after an Indian cobra (Naja naja) bite, developed anaphylaxis, Takotsubo cardiomyopathy, and Kounis syndrome. She was initially diagnosed with acute coronary syndrome after anaphylaxis due to exposure to cobra venom, indicating Kounis syndrome. The echocardiogram, electrocardiogram, and almost complete reversal of dyskinetic myocardium established Takotsubo cardiomyopathy. Adrenaline, initially given for anaphylaxis, and noradrenaline as an intravenous infusion for hypotension potentially precipitated the ATAK complex. The diagnosis was established by history, low blood pressure, elevated troponin, numerous dyskinetic segments in the echocardiogram, and normal coronary vessels in the angiogram.
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