A new benzodioxole derivative from the marine-derived Streptomyces sp. SYPHU 0002

被引：0

作者：

Mou, Pengyun ^{[1
]}

Peng, Yuan ^{[2
]}

Zhang, Bangyan ^{[1
]}

Wang, Pengze ^{[1
]}

Ni, Xianpu ^{[1
]}

Xia, Huanzhang ^{[1
,3
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Life Sci & Biopharmaceut, Benxi, Peoples R China

[2] Guangxi Univ, Coll Anim Sci & Vet Med, Nanning, Peoples R China

[3] Shenyang Pharmaceut Univ, Key Lab Microbial Pharmaceut, Benxi, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2024年

关键词：

Natural product; marine-derived; Streptomyces sp; Antibacterial activity; ANTIFUNGAL;

D O I：

10.1080/14786419.2024.2425058

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

a new benzodioxole derivative 1,3-benzodioxole-2-one-4-N-methylcarboxylamide (1), two new natural products N-(aminocarbonyl)-2,3-dimethoxy-benzamide (2) and 2,3-dimethoxy-N-methylbenzamide (3), along with eight known compounds (4-11), were isolated from the marine-derived Streptomyces sp. SYPHU 0002. The structures of compounds 1-11 were determined through comprehensive spectroscopic analyses, including HRESIMS, 1D and 2D NMR. Compound 9 showed weak antibacterial activity against Bacillus pumilus with the MIC value of 64 mu g mL-1.

引用

页数：7

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