The role of platelet-rich plasma in biomedicine: A comprehensive overview

被引：1
作者：
Zhang, Zhixin [1 ,2 ,3 ,4 ,5 ,6 ]
Liu, Peng [1 ,2 ,3 ,4 ,5 ,6 ]
Xue, Xinmiao [1 ,2 ,3 ,4 ,5 ,6 ]
Zhang, Zhiyu [7 ]
Wang, Li [1 ,2 ,3 ,4 ,5 ,6 ]
Jiang, Yvke [1 ,2 ,3 ,4 ,5 ,6 ]
Zhang, Chi [1 ,2 ,3 ,4 ,5 ,6 ]
Zhou, Hanwen [1 ,2 ,3 ,4 ,5 ]
Lv, Shuhan [1 ,2 ,3 ,4 ,5 ]
Shen, Weidong [1 ,2 ,3 ,4 ,5 ,6 ]
Yang, Shiming [1 ,2 ,3 ,4 ,5 ,6 ]
Wang, Fangyuan [1 ,2 ,3 ,4 ,5 ]
机构：
[1] Chinese PLA Med Sch, Chinese PLA Gen Hosp, Med Ctr 6, Sr Dept Otolaryngol Head & Neck Surg, Beijing 100853, Peoples R China
[2] State Key Lab Hearing & Balance Sci, Beijing 100853, Peoples R China
[3] Natl Clin Res Ctr Otolaryngol Dis, Beijing 100853, Peoples R China
[4] Minist Educ, Key Lab Hearing Sci, Beijing 100853, Peoples R China
[5] Beijing Key Lab Hearing Impairment Prevent & Treat, Beijing 100853, Peoples R China
[6] Chinese Peoples Liberat Army Gen Hosp, Grad Sch Med, Chinese PLA Med Sch, Beijing 100853, Peoples R China
[7] Xidian Univ, Sch Phys & Optoelect Engn, Xian 710071, Peoples R China
来源：
ISCIENCE | 2025年 / 28卷 / 02期
基金：
中国国家自然科学基金;
关键词：
GROWTH-FACTOR; ANDROGENETIC ALOPECIA; KNEE OSTEOARTHRITIS; IMPLANT PLACEMENT; WOUND REPAIR; STEM-CELLS; FIBRIN; SURGERY; MANAGEMENT; BONE;
D O I：
10.1016/j.isci.2024.111705
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Biomedicine has seen significant advancements in the 21st century, with platelet-rich plasma (PRP) playing a crucial role in clinical practice. This blood derivative, enriched with platelet components, has shown great potential for promoting tissue repair and regeneration. Its wide range of applications and the presence of anti-inflammatory and growth-promoting factors make it a valuable tool in the field of biomedicine. The exploration of PRP in clinical settings has been gaining momentum. Despite its cost-effectiveness, safety, and therapeutic efficacy, the widespread clinical adoption of PRP has been hindered by the absence of consistent preparation standards and standardized treatment protocols. This article provides a comprehensive analysis of the clinical uses, physiological roles, molecular mechanisms, and preparation techniques of PRP in biomedicine. The aim is to offer a thorough understanding of the potential applications and benefits of PRP in medical practice.
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页数：19
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