Global research on NK cells in miscarriage: a bibliometric study

被引:0
作者
Wang, Yinan [1 ,2 ]
He, Xiaoqin [3 ]
Yang, Chaogang [4 ,5 ,6 ,7 ]
Ding, Jinli [1 ,2 ]
机构
[1] Wuhan Univ, Reprod Med Ctr, Renmin Hosp, Wuhan, Peoples R China
[2] Hubei Clin Res Ctr Assisted Reprod Technol & Embry, Wuhan, Peoples R China
[3] Wuhan Univ, Renmin Hosp, Teaching Off, Wuhan, Peoples R China
[4] Wuhan Univ, Dept Gastrointestinal Surg, Zhongnan Hosp, Wuhan, Peoples R China
[5] Hubei Key Lab Tumor Biol Behav, Wuhan, Peoples R China
[6] Hubei Canc Clin Study Ctr, Wuhan, Peoples R China
[7] Clin Med Res Ctr Peritoneal Canc Wuhan, Wuhan, Peoples R China
基金
中国国家自然科学基金;
关键词
bibliometric analysis; NK cells; miscarriage; CiteSpace; VOSviewer; NATURAL-KILLER-CELLS; IDIOPATHIC RECURRENT MISCARRIAGE; SPONTANEOUS-ABORTION; MATERNAL KIR; WOMEN; PREGNANCY; PREECLAMPSIA; PREDNISOLONE; PLACEBO; ENDOMETRIUM;
D O I
10.3389/fmed.2025.1513213
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background This study aimed to assess the evolution, trends, and research hotspots of publications related to natural killer (NK) cells and miscarriage. Methods The literature on NK cells and miscarriage was retrieved from the Web of Science Core Collection. VOSviewer and CiteSpace were used to analyze the publication years, countries, institutions, journals, highly cited authors, categories, and citation bursts of keywords. Results A total of 1,275 articles were analyzed. The annual publication outputs showed steady growth, with the majority of publications in 2020 and citations in 2022. The number of publications in this field fluctuated from 1981 to 2023, with a slight downward trend observed. However, the number of citations increased steadily until 2023, followed by a minor decline. The United States contributed the highest number of publications and had the highest h-index. The American Journal of Reproductive Immunology ranked first in terms of number of publications and h-index. Reproductive biology, immunology, and obstetrics and gynecology were the most representative disciplines. Kwak-kim J, Chaouat G, and Croy BA were the top three most productive authors in the field. Keyword burst analysis demonstrated that the immune system and cytotoxicity receptors were current research hotspots. Conclusion This is the first bibliometric study to comprehensively summarize trends and advances in the study of NK cells in miscarriage. This information highlights the recent research frontiers and emerging directions and provides a reference for subsequent research in the future.
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页数:14
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  • [1] Di Nallo A., Koksal S., Job loss during pregnancy and the risk of miscarriage and stillbirth, Hum Reprod, 38, pp. 2259-2266, (2023)
  • [2] Hennessy M., O'Donoghue K., Bridging the gap between pregnancy loss research and policy and practice: insights from a qualitative survey with knowledge users, Health Res Policy Syst, 22, (2024)
  • [3] Quenby S., Gallos I.D., Dhillon-Smith R.K., Podesek M., Stephenson M.D., Fisher J., Et al., Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss, Lancet, 397, pp. 1658-1667, (2021)
  • [4] Du M.X., Li Y.Q., Gu H., Gao M.G., Xu H., Zhong W.Y., Et al., Assessment of the risk of unexplained recurrent spontaneous abortion based on the proportion and correlation of NK cells and T cells in peripheral blood, Technol, Health Care, 31, pp. 97-S109, (2023)
  • [5] Deshmukh H., Way S.S., Immunological basis for recurrent fetal loss and pregnancy complications, Annu Rev Pathol, 14, pp. 185-210, (2019)
  • [6] Zitti B., Bryceson Y.T., Natural killer cells in inflammation and autoimmunity, Cytokine Growth Factor Rev, 42, pp. 37-46, (2018)
  • [7] Mandal A., Viswanathan C., Natural killer cells: in health and disease, Hematol Oncol Stem Cell Ther, 8, pp. 47-55, (2015)
  • [8] Vivier E., Tomasello E., Baratin M., Walzer T., Ugolini S., Functions of natural killer cells, Nat Immunol, 9, pp. 503-510, (2008)
  • [9] Robertson M.J., Ritz J., Biology and clinical relevance of human natural killer cells, Blood, 76, pp. 2421-2438, (1990)
  • [10] Sun J.C., Lanier L.L., Natural killer cells remember: an evolutionary bridge between innate and adaptive immunity?, Eur J Immunol, 39, pp. 2059-2064, (2009)