Association between body roundness index and constipation using data from NHANES 2005–2010

被引：0
作者：
Chaofan Guo [1 ]
Qibo Peng [2 ]
Qi Ao [1 ]
Zhangqiang Zheng [2 ]
Xiangyang Yu [1 ]
机构：
[1] Tianjin NanKai Hospital, Tianjin Medical University, Tianjin
[2] Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Tianjin
来源：
Scientific Reports | / 15卷 / 1期
基金：
中国国家自然科学基金;
关键词：
Body roundness index; Constipation; NHANES; Obesity; Visceral fat;
D O I：
10.1038/s41598-025-96876-w
中图分类号：
学科分类号：
摘要：
Obesity, particularly visceral fat, is a well-established risk factor for various gastrointestinal disorders, including constipation, possibly due to its metabolic and hormonal effects on bowel motility, though the mechanisms remain unclear. The Body Roundness Index (BRI), a novel and reliable anthropometric measure, has been validated as a precise indicator of visceral fat. However, its relationship with constipation remains uncertain. This population-based, cross-sectional study analyzed data from 6,898 participants in the National Health and Nutrition Examination Survey (NHANES, 2005–2010) to assess this association. Binary logistic regression analyses, adjusted for multiple covariates, revealed that higher BRI levels were significantly associated with a lower likelihood of constipation. Participants in the highest quartile had 32% lower odds of constipation than those in the lowest quartile (adjusted OR: 0.68; 95% CI: 0.54–0.86; P: 0.0013). As this was a cross-sectional study, the findings indicate an association between BRI levels and constipation rather than causality. These results suggest that BRI could be a practical and accessible marker for identifying individuals with different susceptibility to constipation, potentially aiding clinical assessment and guiding preventive strategies. © The Author(s) 2025.
引用
收藏
相关论文
共 38 条
  • [11] Chen K., Et al., Prevalence of obesity and associated complications in China: A cross-sectional, real-world study in 15.8 million adults, Diabetes Obes. Metab, 25, 11, pp. 3390-3399, (2023)
  • [12] Delgado-Aros S., Et al., 3rd: obesity is associated with increased risk of Gastrointestinal symptoms: a population-based study, Am. J. Gastroenterol, 99, 9, pp. 1801-1806, (2004)
  • [13] Talley N.J., Howell S., Poulton R., Obesity and chronic Gastrointestinal tract symptoms in young adults: a birth cohort study, Am. J. Gastroenterol, 99, 9, pp. 1807-1814, (2004)
  • [14] Xiang N., Xu L., Qian H., Zhang D., Multiple obesity indices suggest a close relationship between obesity and constipation: evidence from NHANES, BMC Public. Health, 24, 1, (2024)
  • [15] Yang X., Et al., Association between visceral adiposity index and bowel habits and inflammatory bowel disease: a cross-sectional study, Sci. Rep, 14, 1, (2024)
  • [16] Wan Y., Et al., The impact of visceral obesity on chronic constipation, inflammation, immune function and cognitive function in patients with inflammatory bowel disease, Aging, 13, 5, pp. 6702-6711, (2021)
  • [17] Zazai R., Wilms B., Ernst B., Thurnheer M., Schultes B., Waist circumference and related anthropometric indices are associated with metabolic traits in severely obese subjects, Obes. Surg, 24, 5, pp. 777-782, (2014)
  • [18] Jablonowska-Lietz B., Wrzosek M., Wlodarczyk M., Nowicka G., New indexes of body fat distribution, visceral adiposity index, body adiposity index, waist-to-height ratio, and metabolic disturbances in the obese, Kardiologia Polska, 75, 11, pp. 1185-1191, (2017)
  • [19] Yumuk V., Et al., European guidelines for obesity management in adults, Obes. Facts, 8, 6, pp. 402-424, (2015)
  • [20] Salmon-Gomez L., Catalan V., Fruhbeck G., Gomez-Ambrosi J., Relevance of body composition in phenotyping the obesities, Reviews Endocr. Metabolic Disorders, 24, 5, pp. 809-823, (2023)
1234