Effective Synthesis of 5-Amino-1-pentanol via Selective Hydrogenolysis of Biomass-Derived Furfurylamine on Supported Platinum Catalysts at Ambient Temperature

5-Amino-1-pentanol (APO) is an important nitrogen-containing chemical with versatile applications. However, its synthesis is still not efficient. Here, we report the synthesis of APO from biomass-derived furfurylamine (FAM) via the direct cleavage of its alpha-C-O bond neighboring the -CH2NH2 group at ambient temperature. Pt/TiO2 catalysts exhibited high efficiency and stability in the FAM hydrogenolysis to APO, affording a high yield of 85.4% at 30 degrees C and 2.0 MPa of H2 in water. The high efficiency of Pt/TiO2 was found to be related to its superior activity for the cleavage of the alpha-C-O bond in FAM, relative to the hydrogenation of the furan ring on the corner and edge sites of the Pt surfaces. This work provides a viable approach for the precise cleavage of the alpha-C-O bond neighboring the -CH2NH2 group in the furan ring under mild conditions toward the efficient production of APO and its derivatives.