Safety and tolerability of durvalumab (D) plus carboplatin/paclitaxel (CP) plus bevacizumab (B) followed by D, B plus olaparib (O) maintenance (mtx) in patients (pts) with newly diagnosed advanced ovarian cancer (AOC) without a tumour BRCA1/BRCA2 mutation (non-tBRCAm) in the phase III DUO-O trial

被引：0

作者：

Aghajanian, C. ^{[1
,2
]}

Schmalfeldt, B. ^{[3
,4
]}

Okamoto, A. ^{[5
,6
]}

Reuss, A. ^{[7
,8
]}

Kim, J-W. ^{[9
,10
]}

Ospina, G. Marquina ^{[11
,12
]}

Ayhan, A. ^{[13
,14
]}

Salutari, V. ^{[15
,16
]}

Lebreton, C. ^{[17
,18
]}

Labudovic, D. ^{[19
,20
]}

Tognon, G. ^{[21
,22
]}

Chudecka-Glaz, A. M. ^{[23
,24
]}

Berger, R. ^{[25
,26
]}

Lheureux, S. ^{[27
,28
]}

Henry, S. ^{[29
,30
]}

Burges, A. ^{[31
,32
]}

Wenham, R. M. ^{[33
,34
]}

Nishio, S. ^{[35
,36
]}

Marshall, L. ^{[37
]}

Harter, P. ^{[38
,39
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Gynaecol Med Oncol Serv, New York, NY USA

[2] GOG F, New York, NY USA

[3] Univ Kinikum Hamburg Eppendorf, Klin & Poliklin Gynakol, Hamburg, Germany

[4] AGO, Hamburg, Germany

[5] Jikei Univ, Dept Obstet & Gynecol, Sch Med, Tokyo, Japan

[6] JGOG, Tokyo, Japan

[7] Philipps Univ Marburg, Dept Marburg Biometry, Coordinating Ctr Clin Trials, Marburg, Germany

[8] ENGOT, Marburg, Germany

[9] Seoul Natl Univ Hosp, Dept Obstet & Gynaecol, Seoul, South Korea

[10] KGOG, Seoul, South Korea

[11] Hosp Clin San Carlos, Dept Med Oncol, Madrid, Spain

[12] GEICO, Madrid, Spain

[13] Baskent Univ Hosp, Div Gynecol Oncol, Dept Obstet & Gynecol, Ankara, Turkiye

[14] TRSGO, Ankara, Turkiye

[15] Fdn Policlin A Gemelli IRCCS, Dept Gynaecol Oncol, Rome, Italy

[16] MITO, Rome, Italy

[17] Inst Bergonie, Dept Oncol Med, Grp Gynecol, Bordeaux, France

[18] GINECO, Bordeaux, France

[19] Sjaelland Univ Hosp, Dept Clin Oncol & Palliat Care, Roskilde, Denmark

[20] NSGO, Roskilde, Denmark

[21] ASST Spedali Civili Brescia, Dept Obstet & Gynecol, Brescia, Italy

[22] MaNGO, Brescia, Italy

[23] Pomorskiego Uniwersytetu Medycznego, Samodzielny Publiczny Szpital Kliniczny 2, Dept Gynecol Surg & Gynecol Oncol Adults & Adoles, Szczecin, Poland

[24] PGOG, Szczecin, Poland

[25] Med Univ Innsbruck, Dept Obstet & Gynecol, Innsbruck, Austria

[26] AGO AU, Innsbruck, Austria

[27] Princess Margaret Hosp, Dept Med Oncol, Toronto, ON, Canada

[28] PMHC, Toronto, ON, Canada

[29] CHU UCL Site Ste Elisabeth, Med Oncol Dept, Namur, Belgium

[30] BGOG, Namur, Belgium

[31] LMU Klinikum, Dept Obstet & Gynecol, Munich, Germany

[32] AGO, Munich, Germany

[33] H Lee Moffitt Canc Ctr & Res Inst, Dept Gynecol Oncol, Tampa, FL USA

[34] GOG F, Tampa, FL USA

[35] Kurume Univ, Sch Med, Dept Obstet & Gynecol, Kurume, Fukuoka, Japan

[36] JGOG, Kurume, Fukuoka, Japan

[37] AstraZeneca, Oncol R&D, Global Med Dev, Luton, Beds, England

[38] Kliniken Essen Mitte, Dept Gynecol & Gynecol Oncol, Essen, Germany

[39] AGO, Essen, Germany

来源：

ANNALS OF ONCOLOGY | 2024年 / 35卷

关键词：

D O I：

10.1016/j.annonc.2024.08.812

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

751P

引用

页码：S570 / S571

页数：2