Association of omega-3 polyunsaturated fatty acids intake and cognitive function in middle-aged and older adults

被引:0
作者
Naaman, Rouba Khalil [1 ]
Alashmali, Shoug [1 ]
Bakhsh, Manar Abduljalil [1 ,2 ]
Muqaibil, Asma Abdullah [1 ]
Ghunaim, Futooun Mohammed [1 ]
Alattas, Albatol Hussein [1 ]
机构
[1] King Abdulaziz Univ, Fac Appl Med Sci, Dept Clin Nutr, Jeddah, Saudi Arabia
[2] Kings Coll London, Dept Women & Childrens Hlth, London, England
关键词
Omega-3; PUFA; cognition; MoCA; elderly; middle-aged adults; aging; Saudi Arabia; SUPPLEMENTATION; OMEGA-3-FATTY-ACIDS; PREVENTION; BENEFITS; DISEASE; HEALTH; TRANSLATION; NUTRITION; DEMENTIA; DECLINE;
D O I
10.1080/1028415X.2024.2404785
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Objective: Omega-3 polyunsaturated fatty acids (PUFAs) play a crucial role in maintaining and improving cognitive function and brain health. The aim of this study was to assess the association between omega-3 PUFA intake and cognitive function in middle-aged and older adults in Saudi Arabia. Methods: Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA). The frequency and quantity of omega-3 PUFA intake were assessed using an omega-3 food frequency questionnaire. Results: A total of 175 participants were recruited for this study. Participants in the lowest omega-3 PUFA tertile group scored significantly lower in the visuospatial/executive and attention cognitive domains (p < 0.05). After adjusting for confounders, the higher intake of alpha-linolenic acid (ALA) was significantly associated with higher scores in the visuospatial/executive domain (p = 0.02) and the higher intake of docosahexaenoic acid (DHA) was significantly associated with higher scores in the attention domain (p = 0.04). The participants who did not consume walnuts showed a significant lower MoCA score than those who did (p = 0.005). No significant differences were found with other omega-3 PUFA sources. Conclusion: Higher intake of omega-3 PUFAs was positively associated with visuospatial/executive and attention cognitive functions in middle-aged and older adults.
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页数:10
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