Pathogenesis of Alcohol-Associated Liver Disease

被引:3
作者
Mandrekar, Pranoti [1 ]
Mandal, Abhishek [1 ]
机构
[1] Univ Massachusetts, Chan Med Sch, Dept Med, 364 Plantat St, Worcester, MA 01605 USA
关键词
Alcohol associated liver disease; Pathogenesis; Fatty liver; Inflammation; Cytokines; Chemokines; Immune cells; Interorgan crosstalk; NATURAL-KILLER-CELLS; MACROPHAGE ACTIVATION; ADIPOSE-TISSUE; ETHANOL; HEPATITIS; INJURY; STEATOSIS; PATHWAY; STRESS; MICE;
D O I
10.1016/j.cld.2024.06.005
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:647 / 661
页数:15
相关论文
共 76 条
  • [1] Hepatocyte dedifferentiation profiling in alcohol-related liver disease identifies CXCR4 as a driver of cell reprogramming
    Aguilar-Bravo, Beatriz
    Arino, Silvia
    Blaya, Delia
    Pose, Elisa
    de la Torre, Raquel A. Martinez Garcia
    Latasa, Maria U.
    Martinez-Sanchez, Celia
    Zanatto, Laura
    Sererols-Vinas, Laura
    Cantallops-Vila, Paula
    Affo, Silvia
    Coll, Mar
    Thillen, Xavier
    Dubuquoy, Laurent
    Avila, Matias A.
    Argemi, Josepmaria
    Paz, Arantza Lamas
    Nevzorova, Yulia A.
    Cubero, Francisco Javier
    Bataller, Ramon
    Lozano, Juan Jose
    Gines, Pere
    Mathurin, Philippe
    Sancho-Bru, Pau
    [J]. JOURNAL OF HEPATOLOGY, 2023, 79 (03) : 728 - 740
  • [2] Decreased Peripheral Blood CD4+/CD25+ Regulatory T Cells in Patients with Alcoholic Hepatitis
    Almeida, Julia
    Angeles Polvorosa, Maria
    Gonzalez-Quintela, Arturo
    Marcos, Miguel
    Pastor, Isabel
    Hernandez Cerceno, Maria Luisa
    Orfao, Alberto
    Laso, Francisco-Javier
    [J]. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2013, 37 (08) : 1361 - 1369
  • [3] Alcohol Abstinence in Patients Surviving an Episode of Alcoholic Hepatitis: Prediction and Impact on Long-Term Survival
    Altamirano, Jose
    Lopez-Pelayo, Hugo
    Michelena, Javier
    Jones, Patricia D.
    Ortega, Lluisa
    Gines, Pere
    Caballeria, Juan
    Gual, Antoni
    Bataller, Ramon
    Lligona, Anna
    [J]. HEPATOLOGY, 2017, 66 (06) : 1842 - 1853
  • [4] Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury
    Ambade, Aditya
    Catalano, Donna
    Lim, Arlene
    Kopoyan, Andre
    Shaffer, Scott A.
    Mandrekar, Pranoti
    [J]. JOURNAL OF HEPATOLOGY, 2014, 61 (04) : 903 - 911
  • [5] Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice
    Ambade, Aditya
    Catalano, Donna
    Lim, Arlene
    Mandrekar, Pranoti
    [J]. HEPATOLOGY, 2012, 55 (05) : 1585 - 1595
  • [6] An Open-Label, Dose-Escalation Study to Assess the Safety and Efficacy of IL-22 Agonist F-652 in Patients With Alcohol-associated Hepatitis
    Arab, Juan P.
    Sehrawat, Tejasav S.
    Simonetto, Douglas A.
    Verma, Vikas K.
    Feng, Dechun
    Tang, Tom
    Dreyer, Kevin
    Yan, Xiaoqiang
    Daley, William L.
    Sanyal, Arun
    Chalasani, Naga
    Radaeva, Svetlana
    Yang, Liu
    Vargas, Hugo
    Ibacache, Mauricio
    Gao, Bin
    Gores, Gregory J.
    Malhi, Harmeet
    Kamath, Patrick S.
    Shah, Vijay H.
    [J]. HEPATOLOGY, 2020, 72 (02) : 441 - 453
  • [7] Integrated Transcriptomic and Proteomic Analysis Identifies Plasma Biomarkers of Hepatocellular Failure in Alcohol-Associated Hepatitis
    Argemi, Josepmaria
    Kedia, Komal
    Gritsenko, Marina A.
    Clemente-Sanchez, Ana
    Asghar, Aliya
    Herranz, Jose M.
    Liu, Zhang-Xu
    Atkinson, Stephen R.
    Smith, Richard D.
    Norden-Krichmar, Trina M.
    Day, Le Z.
    Stolz, Andrew
    Tayek, John A.
    Bataller, Ramon
    Morgan, Timothy R.
    Jacobs, Jon M.
    [J]. AMERICAN JOURNAL OF PATHOLOGY, 2022, 192 (12) : 1658 - 1669
  • [8] Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
    Argemie, Josepmaria
    Latasa, Maria U.
    Atkinson, Stephen R.
    Blokhin, Ilya O.
    Massey, Veronica
    Gue, Joel P.
    Cabezas, Joaquin
    Lozano, Juan J.
    Van Booven, Derek
    Bell, Aaron
    Cao, Sheng
    Vernetti, Lawrence A.
    Arab, Juan P.
    Ventura-Cots, Meritxell
    Edmunds, Lia R.
    Fondevilla, Constantino
    Starkel, Peter
    Dubuquoy, Laurent
    Louvet, Alexandre
    Odena, Gemma
    Gomez, Juan L.
    Aragon, Tomas
    Altamirano, Jose
    Caballeria, Juan
    Jurczak, Michael J.
    Taylor, D. Lansing
    Berasain, Carmen
    Wahlestedt, Claes
    Mongv, Satdarshan P.
    Morgan, Marsha Y.
    Sancho-Bru, Pau
    Mathurin, Philippe
    Furuya, Shinji
    Lackner, Carolin
    Rusyn, Ivan
    Shah, Vijay H.
    Thursz, Mark R.
    Mann, Jelena
    Avila, Matias A.
    Bataller, Ramon
    [J]. NATURE COMMUNICATIONS, 2019, 10 (1)
  • [9] Alcohol-Associated Hepatitis
    Bataller, Ramon
    Pablo Arab, Juan
    Shah, Vijay H.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2022, 387 (26) : 2436 - 2448
  • [10] Chronic Plus Binge Ethanol Feeding Synergistically Induces Neutrophil Infiltration and Liver Injury in Mice: A Critical Role for E-selectin
    Bertola, Adeline
    Park, Ogyi
    Gao, Bin
    [J]. HEPATOLOGY, 2013, 58 (05) : 1814 - 1823