Contemporary Approach to the Diagnosis and Classification of Myelodysplastic Neoplasms/SyndromesdRecommendations From the International Consortium for Myelodysplastic Neoplasms/Syndromes (MDS [icMDS])

被引：3

作者：

Aakash, Fnu ^{[1
,2
]}

Gisriel, Savanah D. ^{[3
,4
]}

Zeidan, Amer M. ^{[5
]}

Bennett, John M. ^{[6
]}

Bejar, Rafael ^{[7
]}

Bewersdorf, Jan Philipp ^{[8
]}

Borate, Uma M. ^{[9
]}

Boultwood, Jacqueline ^{[10
]}

Brunner, Andrew M. ^{[11
]}

Buckstein, Rena ^{[12
]}

Carraway, Hetty E. ^{[13
]}

Churpek, Jane E. ^{[14
]}

Daver, Naval G. ^{[15
]}

Dezern, Amy E. ^{[16
]}

Efficace, Fabio ^{[17
]}

Fenaux, Pierre ^{[18
]}

Figueroa, Maria E. ^{[19
]}

Garcia-Manero, Guillermo ^{[15
]}

Gore, Steven D. ^{[20
]}

Greenberg, Peter L. ^{[21
]}

Griffiths, Elizabeth A. ^{[22
]}

Halene, Stephanie ^{[5
]}

Hourigan, Christopher S. ^{[23
]}

Kim, Tae Kon ^{[24
]}

Kim, Nina ^{[25
]}

Komrokji, Rami S. ^{[26
]}

Kutchroo, Vijay K. ^{[27
]}

List, Alan F. ^{[28
]}

Little, Richard F. ^{[20
]}

Majeti, Ravindra ^{[21
]}

Nazha, Aziz ^{[29
]}

Nimer, Stephen D. ^{[30
]}

Odenike, Olatoyosi ^{[31
,32
]}

Padron, Eric ^{[26
]}

Patnaik, Mrinal M. ^{[33
]}

Platzbecker, Uwe ^{[34
]}

Porta, Matteo G. Della ^{[35
]}

Roboz, Gail J. ^{[36
,37
]}

Sallman, David A. ^{[26
]}

Santini, Valeria ^{[38
]}

Sanz, Guillermo ^{[39
,40
,41
]}

Savona, Michael R. ^{[24
]}

Sekeres, Mikkael A. ^{[30
]}

Stahl, Maximilian ^{[42
]}

Starczynowski, Daniel T. ^{[43
]}

Steensma, David P. ^{[44
]}

Taylor, Justin ^{[30
]}

Abdel-Wahab, Omar ^{[8
]}

Wei, Andrew H. ^{[45
]}

Xie, Zhuoer ^{[26
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Hematopathol, Houston, TX 77030 USA

[2] Univ Texas Med Branch, Dept Pathol, Galveston, TX USA

[3] Yale Univ, Sch Med, Dept Pathol, New Haven, CT USA

[4] Univ Wisconsin Madison, Dept Pathol & Lab Med, Madison, WI USA

[5] Yale Sch Med, Yale Canc Ctr, Dept Internal Med, Sect Hematol,Sch Med, New Haven, CT USA

[6] Univ Rochester, Med Ctr, James P Wilmot Canc Ctr, Div Hematopathol, Rochester, NY USA

[7] Univ Calif San Diego, Moores Canc Ctr, Div Hematol & Oncol, La Jolla, CA USA

[8] Mem Sloan Kettering Canc Ctr, Dept Med, Leukemia Serv, New York, NY USA

[9] Ohio State Univ, Div Hematol, Comprehens Canc Ctr, Columbus, OH USA

[10] Univ Oxford, Nuffield Div Clin Lab Sci, Radcliffe Dept Med, Oxford, England

[11] Brigham & Womens Hosp, Div Hematol, Boston, MA USA

[12] Sunnybrook Hlth Sci Ctr, Dept Med, Div Med Oncol Hematol, Toronto, ON, Canada

[13] Cleveland Clin, Leukemia Program, Taussig Canc Inst, Hematol & Med Oncol, Cleveland, OH USA

[14] Univ Wisconsin Madison, Carbone Canc Ctr, Div Haematol Oncol & Palliat Care, Madison, WI 53706 USA

[15] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX USA

[16] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA

[17] Italian Grp Adult Hematol Dis GIMEMA, Hlth Outcomes Res Unit, Rome, Italy

[18] Univ Paris Cite, Serv Hematol, Paris, France

[19] Univ Miami, Miller Sch Med, Dept Neurol, Miami, FL 33136 USA

[20] NCI, Canc Therapy Evaluat Program, Rockville, MD USA

[21] Stanford Univ, Stanford Canc Inst, Sch Med, Dept Med,Div Hematol, Stanford, CA USA

[22] Roswell Park Comprehens Canc Ctr, Buffalo, NY USA

[23] Virginia Tech, Fralin Biomed Res Inst, FBRI Canc Res Ctr, Washington, DC USA

[24] Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Dept Med, Nashville, TN USA

[25] NCI, NIH, Bethesda, MD USA

[26] H Lee Moffitt Canc Ctr & Res Inst, Malignant Hematol Program, Tampa, FL USA

[27] Brigham & Womens Hosp, Boston, MA USA

[28] New York Infirm, New York, NY USA

[29] Thomas Jefferson Univ, Sidney Kimmel Med Coll, Philadelphia, PA USA

[30] Univ Miami, Dept Med, Div Hematol, Div Hematol,Miller Sch Med, Miami, FL USA

[31] Univ Chicago, Sect Hematol Oncol, Leukemia Program, Chicago, IL 60637 USA

[32] Univ Chicago, Comprehens Canc Ctr, Chicago, IL USA

[33] Mayo Clin, Dept Internal Med, Div Hematol, Rochester, MN USA

[34] Univ Hosp Leipzig, Dept Hematol & Cellular Therapy, Leipzig, Germany

[35] Humanitas Univ, Dept Biomed Sci, Milan, Italy

[36] New York Acad Med, New York, NY USA

[37] New York Presbyterian Hosp, New York, NY USA

[38] Univ Florence, Dept Expt & Clin Med, Myelodysplast Syndromes Unit, Hematol,Azienda Osped Univ Careggi, Florence, Italy

[39] Hlth Res Inst La Fe, Valencia, Spain

[40] Hosp Univ & Politecn La Fe, Valencia, Spain

[41] ISCarlosIII, CIBERONC, Madrid, Spain

[42] Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, Div Leukemia, Boston, MA USA

[43] Cincinnati Childrens Hosp, Div Expt Hematol & Canc Biol, Cincinnati, OH USA

[44] David Steensma LLC, Cambridge, MA USA

[45] Royal Melbourne Hosp, Dept Haematol Lab, Walter & Eliza Hall Inst Med Res, Melbourne, Vic, Australia

[46] Massachusetts Gen Hosp Brigham, Dept Pathol, Boston, MA USA

来源：

MODERN PATHOLOGY | 2024年 / 37卷 / 12期

基金：

美国国家卫生研究院;

关键词：

icMDS; MDS; myelodysplastic neoplasms; myelodysplastic syndromes; classification; diagnosis; HEALTH-ORGANIZATION CLASSIFICATION; FLOW-CYTOMETRY; COPPER DEFICIENCY; 5TH EDITION; MUTATIONS; VALIDATION; RISK; ABNORMALITIES; EVOLUTION; LEUKEMIA;

D O I：

10.1016/j.modpat.2024.100615

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Myelodysplastic neoplasms/syndromes (MDS) are a heterogeneous group of biologically distinct entities characterized by variable degrees of ineffective hematopoiesis. Recently, 2 classification systems (the 5th edition of the World Health Organization Classification of Haematolymphoid tTumours and the International Consensus Classification) further subcharacterized MDS into morphologically and genetically defined groups. Accurate diagnosis and subclassification of MDS require a multistep systemic approach. The International Consortium for MDS (icMDS) summarizes a contemporary, practical, and multimodal approach to MDS diagnosis and classification. (c) 2024 United States & Canadian Academy of Pathology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

引用

页数：13

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