MR-Guided PET Reconstruction

被引：0

作者：

Huellner, Martin W. ^{[1
]}

Maurer, Alexander ^{[1
]}

Spangler-Bickell, Matthew ^{[2
]}

机构：

[1] Univ Zurich, Univ Hosp Zurich, Dept Nucl Med, Raemistr 100, CH-8091 Zurich, Switzerland

[2] GE Healthcare, Waukesha, WI USA

来源：

CLINICAL NUCLEAR MEDICINE | 2025年 / 50卷 / 03期

关键词：

epilepsy; seizure; mesiotemporal sclerosis; F-18-FDG; PET/CT; image reconstruction; F-18-FDG PET; EPILEPSY;

D O I：

10.1097/RLU.0000000000005631

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We report a case of a 33-year-old man with epilepsy and equivocal EEG, MRI signs of mesiotemporal sclerosis, and nondiagnostic standard FDG-PET imaging. The patient underwent repeat FDG-PET/MRI to clarify the sidedness of the epileptogenic focus and to confirm the suspected MTS. The standard PET reconstruction using block sequential regularized expectation maximization failed to provide evidence of a clear epileptogenic focus. However, using MR-guided PET reconstruction, circumscribed hypometabolism was observed in the right-sided entorhinal cortex, compatible with the epileptogenic focus. The MR-guided PET reconstruction provided significantly improved gray/white matter differentiation, enhancing confidence in imaging interpretation.

引用

页码：271 / 272

页数：2

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