MR-Guided PET Reconstruction

被引：0

作者：

Huellner, Martin W. ^{[1
]}

Maurer, Alexander ^{[1
]}

Spangler-Bickell, Matthew ^{[2
]}

机构：

[1] Univ Zurich, Univ Hosp Zurich, Dept Nucl Med, Raemistr 100, CH-8091 Zurich, Switzerland

[2] GE Healthcare, Waukesha, WI USA

来源：

CLINICAL NUCLEAR MEDICINE | 2025年 / 50卷 / 03期

关键词：

epilepsy; seizure; mesiotemporal sclerosis; F-18-FDG; PET/CT; image reconstruction; F-18-FDG PET; EPILEPSY;

D O I：

10.1097/RLU.0000000000005631

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We report a case of a 33-year-old man with epilepsy and equivocal EEG, MRI signs of mesiotemporal sclerosis, and nondiagnostic standard FDG-PET imaging. The patient underwent repeat FDG-PET/MRI to clarify the sidedness of the epileptogenic focus and to confirm the suspected MTS. The standard PET reconstruction using block sequential regularized expectation maximization failed to provide evidence of a clear epileptogenic focus. However, using MR-guided PET reconstruction, circumscribed hypometabolism was observed in the right-sided entorhinal cortex, compatible with the epileptogenic focus. The MR-guided PET reconstruction provided significantly improved gray/white matter differentiation, enhancing confidence in imaging interpretation.

引用

页码：271 / 272

页数：2

共 15 条

[1] A solution to PET brain motion artefact [J].

Bradley, Kevin M. ;

Deller, Timothy W. ;

Spangler-Bickell, Matthew G. ;

Jansen, Floris P. ;

McGowan, Daniel R. .

JOURNAL OF NEUROLOGY, 2021, 268 (09) :3476-3477

[2] Anti-LGI1 Autoimmune Epilepsy [J].

Burkett, Brian J. ;

Johnson, Derek R. ;

Hunt, Christopher H. ;

Messina, Steven A. ;

Broski, Stephen M. .

CLINICAL NUCLEAR MEDICINE, 2023, 48 (11) :956-957

[3] Prevalence of Nonlesional Focal Epilepsy in an Adult Epilepsy Clinic [J].

Dang Khoa Nguyen ;

Mbacfou, Manuela Temgoua ;

Dong Bach Nguyen ;

Lassonde, Maiyse .

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2013, 40 (02) :198-202

[4] The evaluation of FDG-PET imaging for epileptogenic focus localization in patients with MRI positive and MRI negative temporal lobe epilepsy [J].

Gok, Beril ;

Jallo, George ;

Hayeri, Reza ;

Wahl, Richard ;

Aygun, Nafi .

NEURORADIOLOGY, 2013, 55 (05) :541-550

[5] An Independent Seizure-Onset Zone in Medial Temporal Lobe Found by 18F-FDG PET Imaging Besides Epileptogenic Periventricular Nodular Heterotopia [J].

Guo, Ruijie ;

Jin, Liri ;

Dou, Wanchen ;

Liu, Linwen ;

Cui, Ruixue .

CLINICAL NUCLEAR MEDICINE, 2022, 47 (09) :841-842

[6] No Evidence to Favor 99mTc-HMPAO or 99mTc-ECD for Ictal Brain Perfusion SPECT for Identification of the Seizure Onset Zone [J].

Jaber, Mariam ;

Taherpour, Jila ;

Voges, Berthold ;

Apostolova, Ivayla ;

Sauvigny, Thomas ;

House, Patrick M. ;

Lanz, Michael ;

Lindenau, Matthias ;

Klutmann, Susanne ;

Martens, Tobias ;

Stodieck, Stefan ;

Buchert, Ralph .

CLINICAL NUCLEAR MEDICINE, 2021, 46 (11) :890-895

[7]

Khalighi MM., 2023, Feature Space Based MR Guided PET Reconstruction. US Patent 11,672, P12

[8] Glucose Metabolism of Hippocampal Subfields in Medial Temporal Lobe Epilepsy [J].

Lee, Tse-Hao ;

Shih, Yen-Cheng ;

Lu, Yi-Jiun ;

Chou, Chien-Chen ;

Lee, Cheng-Chia ;

Yu, Hsiang-Yu ;

Peng, Syu-Jyun .

CLINICAL NUCLEAR MEDICINE, 2024, 49 (04) :294-300

[9] Diagnostic Superiority of 18F-FDG PET Over MRI in Detecting Anti-LGI1 Autoimmune Encephalitis: A Comparative Study With Insights Into Faciobrachial Dystonic Seizures Mechanisms and Recurrence Identification [J].

Liang, Menglin ;

Niu, Na ;

Jia, Chenhao ;

Fan, Siyuan ;

Liu, Linwen ;

Cui, Ruixue ;

Guan, Hongzhi .

CLINICAL NUCLEAR MEDICINE, 2023, 48 (11) :E516-E522

[10] Advanced Imaging Techniques in the Diagnosis of Nonlesional Epilepsy: MRI, MRS, PET, and SPECT [J].

Pardoe, Heath ;

Kuzniecky, Ruben .

EPILEPSY CURRENTS, 2014, 14 (03) :121-124

← 1 2 →