Neurophysiological markers of early cognitive decline in older adults: a mini-review of electroencephalography studies for precursors of dementia

被引:3
作者
Tanaka, Mutsuhide [1 ]
Yamada, Emi [2 ]
Mori, Futoshi [1 ]
机构
[1] Prefectural Univ Hiroshima, Fac Hlth & Welf, Dept Hlth & Welf Occupat Therapy Course, Hiroshima, Japan
[2] Kyushu Univ, Fac Humanities, Dept Linguist, Fukuoka, Japan
关键词
electroencephalogram (EEG); event-related potentials (ERPs); dementia prevention; neurophysiological biomarker; mild cognitive impairment; subjective cognitive decline; subjective memory complaint; cognitive frailty; SUBJECTIVE MEMORY COMPLAINTS; RESTING-STATE EEG; ALZHEIMERS-DISEASE; MISMATCH NEGATIVITY; ALPHA RHYTHMS; N200; LATENCY; IMPAIRMENT; P300; CONNECTIVITY; METAANALYSIS;
D O I
10.3389/fnagi.2024.1486481
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
The early detection of cognitive decline in older adults is crucial for preventing dementia. This mini-review focuses on electroencephalography (EEG) markers of early dementia-related precursors, including subjective cognitive decline, subjective memory complaints, and cognitive frailty. We present recent findings from EEG analyses identifying high dementia risk in older adults, with an emphasis on conditions that precede mild cognitive impairment. We also cover event-related potentials, quantitative EEG markers, microstate analysis, and functional connectivity approaches. Moreover, we discuss the potential of these neurophysiological markers for the early detection of cognitive decline as well as their correlations with related biomarkers. The integration of EEG data with advanced artificial intelligence technologies also shows promise for predicting the trajectory of cognitive decline in neurodegenerative disorders. Although challenges remain in its standardization and clinical application, EEG-based approaches offer non-invasive, cost-effective methods for identifying individuals at risk of dementia, which may enable earlier interventions and personalized treatment strategies.
引用
收藏
页数:10
相关论文
共 105 条
[21]  
Devos H., 2021, Alzheimers Dement, V17, DOI [10.1002/alz.052418, DOI 10.1002/ALZ.052418]
[22]   Predicting Dementia With Prefrontal Electroencephalography and Event-Related Potential [J].
Doan, Dieu Ni Thi ;
Ku, Boncho ;
Choi, Jungmi ;
Oh, Miae ;
Kim, Kahye ;
Cha, Wonseok ;
Kim, Jaeuk U. .
FRONTIERS IN AGING NEUROSCIENCE, 2021, 13
[23]   The Power of EEG to Predict Conversion from Mild Cognitive Impairment and Subjective Cognitive Decline to Dementia [J].
Engedal, Knut ;
Barca, Maria Lage ;
Hogh, Peter ;
Andersen, Birgitte Bo ;
Dombernowsky, Nanna Winther ;
Naik, Mala ;
Gudmundsson, Thorkell Eli ;
Oksengaard, Anne-Rita ;
Wahlund, Lars-Olof ;
Snaedal, Jon .
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2020, 49 (01) :38-47
[24]   Cognitive Frailty: An Update [J].
Facal, David ;
Burgo, Clara ;
Spuch, Carlos ;
Gaspar, Pedro ;
Campos-Magdaleno, Maria .
FRONTIERS IN PSYCHOLOGY, 2021, 12
[25]   A comparison of resting state Alzheimer ?s disease and mild EEG and structural MRI for classifying cognitive impairment [J].
Farina, F. R. ;
Emek-Savas, D. D. ;
Rueda-Delgado, L. ;
Boyle, R. ;
Kiiski, H. ;
Yener, G. ;
Whelan, R. .
NEUROIMAGE, 2020, 215
[26]   EEG Alpha and Beta Band Functional Connectivity and Network Structure Mark Hub Overload in Mild Cognitive Impairment During Memory Maintenance [J].
Fodor, Zsuzsanna ;
Horvath, Andras ;
Hidasi, Zoltan ;
Gouw, Alida A. ;
Stam, Cornelis J. ;
Csukly, Gabor .
FRONTIERS IN AGING NEUROSCIENCE, 2021, 13
[27]   Associations of event-related brain potentials and Alzheimer's disease severity: A longitudinal study [J].
Fruehwirt, Wolfgang ;
Dorffner, Georg ;
Roberts, Stephen ;
Gerstgrasser, Matthias ;
Grossegger, Dieter ;
Schmidt, Reinhold ;
Dal-Bianco, Peter ;
Ransmayr, Gerhard ;
Garn, Heinrich ;
Waser, Markus ;
Benke, Thomas .
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2019, 92 :31-38
[28]   A new and short protocol to achieve the early diagnosis of mild cognitive impairment [J].
Garcia, Sara ;
Cuetos, Fernando ;
Novelli, Antonello ;
Martinez, Carmen .
NEUROLOGICAL SCIENCES, 2021, 42 (09) :3687-3694
[29]   Subjective Memory Complaints and Decision Making in Young and Older Adults: An Event-Related Potential Study [J].
Garrido-Chaves, Ruth ;
Perez, Vanesa ;
Perez-Alarcon, Mario ;
Crespo-Sanmiguel, Isabel ;
Paiva, Tiago O. ;
Hidalgo, Vanesa ;
Pulopulos, Matias M. ;
Salvador, Alicia .
FRONTIERS IN AGING NEUROSCIENCE, 2021, 13
[30]   Usefulness of P300 in subjective memory complaints -: A prospective study [J].
Gironell, A ;
Garcia-Sánchez, C ;
Estévez-González, A ;
Boltes, A ;
Kulisevsky, J .
JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2005, 22 (04) :279-284