Neurophysiological markers of early cognitive decline in older adults: a mini-review of electroencephalography studies for precursors of dementia

被引:0
作者
Tanaka, Mutsuhide [1 ]
Yamada, Emi [2 ]
Mori, Futoshi [1 ]
机构
[1] Prefectural Univ Hiroshima, Fac Hlth & Welf, Dept Hlth & Welf Occupat Therapy Course, Hiroshima, Japan
[2] Kyushu Univ, Fac Humanities, Dept Linguist, Fukuoka, Japan
来源
FRONTIERS IN AGING NEUROSCIENCE | 2024年 / 16卷
关键词
electroencephalogram (EEG); event-related potentials (ERPs); dementia prevention; neurophysiological biomarker; mild cognitive impairment; subjective cognitive decline; subjective memory complaint; cognitive frailty; SUBJECTIVE MEMORY COMPLAINTS; RESTING-STATE EEG; ALZHEIMERS-DISEASE; MISMATCH NEGATIVITY; ALPHA RHYTHMS; N200; LATENCY; IMPAIRMENT; P300; CONNECTIVITY; METAANALYSIS;
D O I
10.3389/fnagi.2024.1486481
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
The early detection of cognitive decline in older adults is crucial for preventing dementia. This mini-review focuses on electroencephalography (EEG) markers of early dementia-related precursors, including subjective cognitive decline, subjective memory complaints, and cognitive frailty. We present recent findings from EEG analyses identifying high dementia risk in older adults, with an emphasis on conditions that precede mild cognitive impairment. We also cover event-related potentials, quantitative EEG markers, microstate analysis, and functional connectivity approaches. Moreover, we discuss the potential of these neurophysiological markers for the early detection of cognitive decline as well as their correlations with related biomarkers. The integration of EEG data with advanced artificial intelligence technologies also shows promise for predicting the trajectory of cognitive decline in neurodegenerative disorders. Although challenges remain in its standardization and clinical application, EEG-based approaches offer non-invasive, cost-effective methods for identifying individuals at risk of dementia, which may enable earlier interventions and personalized treatment strategies.
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页数:10
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共 105 条
  • [1] Entropy analysis of the EEG background activity in Alzheimer's disease patients
    Abásolo, D
    Hornero, R
    Espino, P
    Alvarez, D
    Poza, J
    [J]. PHYSIOLOGICAL MEASUREMENT, 2006, 27 (03) : 241 - 253
  • [2] Factors predicting episodic memory changes in older adults with subjective cognitive decline: A longitudinal observational study
    Ahn, Sangwoo
    Mathiason, Michelle A.
    Lindquist, Ruth
    Yu, Fang
    [J]. GERIATRIC NURSING, 2021, 42 (01) : 268 - 275
  • [3] Al-Hagery M. A., 2020, Indones. J. Electr. Eng. Inform, V8, DOI [10.52549/ijeei.v8i1.1321, DOI 10.52549/IJEEI.V8I1.1321]
  • [4] Role of EEG as Biomarker in the Early Detection and Classification of Dementia
    Al-Qazzaz, Noor Kamal
    Ali, Sawal Hamid Bin Md
    Ahmad, Siti Anom
    Chellappan, Kalaivani
    Islam, Md. Shabiul
    Escudero, Javier
    [J]. SCIENTIFIC WORLD JOURNAL, 2014,
  • [5] Neuronal hyperexcitability in Alzheimer's disease: what are the drivers behind this aberrant phenotype?
    Anastacio, Helena Targa Dias
    Matosin, Natalie
    Ooi, Lezanne
    [J]. TRANSLATIONAL PSYCHIATRY, 2022, 12 (01)
  • [6] Synaptic degeneration in Alzheimer's disease
    Arendt, Thomas
    [J]. ACTA NEUROPATHOLOGICA, 2009, 118 (01) : 167 - 179
  • [7] Neuropsychological features of mild cognitive impairment and preclinical Alzheimer's disease
    Arnáiz, E
    Almkvist, O
    [J]. ACTA NEUROLOGICA SCANDINAVICA, 2003, 107 : 34 - 41
  • [8] Resting State Alpha Electroencephalographic Rhythms Are Differently Related to Aging in Cognitively Unimpaired Seniors and Patients with Alzheimer's Disease and Amnesic Mild Cognitive Impairment
    Babiloni, Claudio
    Ferri, Raffaele
    Noce, Giuseppe
    Lizio, Roberta
    Lopez, Susanna
    Lorenzo, Ivan
    Tucci, Federico
    Soricelli, Andrea
    Nobili, Flavio
    Arnaldi, Dario
    Fama, Francesco
    Orzi, Francesco
    Buttinelli, Carla
    Giubilei, Franco
    Cipollini, Virginia
    Marizzoni, Moira
    Guntekin, Bahar
    Akturk, Tuba
    Hanoglu, Lutfu
    Yener, Gorsev
    Ozbek, Yagmur
    Stocchi, Fabrizio
    Vacca, Laura
    Frisoni, Giovanni B.
    Del Percio, Claudio
    [J]. JOURNAL OF ALZHEIMERS DISEASE, 2021, 82 (03) : 1085 - 1114
  • [9] Resting-state posterior alpha rhythms are abnormal in subjective memory complaint seniors with preclinical Alzheimer's neuropathology and high education level: the INSIGHT-preAD study
    Babiloni, Claudio
    Lopez, Susanna
    Del Percio, Claudio
    Noce, Giuseppe
    Pascarelli, Maria Teresa
    Lizio, Roberta
    Teipel, Stefan J.
    Gonzalez-Escamilla, Gabriel
    Bakardjian, Hovagim
    George, Nathalie
    Cavedo, Enrica
    Lista, Simone
    Chiesa, Patrizia Andrea
    Vergallo, Andrea
    Lemercier, Pablo
    Spinelli, Giuseppe
    Grothe, Michel J.
    Potier, Marie-Claude
    Stocchi, Fabrizio
    Ferri, Raffaele
    Habert, Marie-Odile
    Fraga, Francisco J.
    Dubois, Bruno
    Hampel, Harald
    [J]. NEUROBIOLOGY OF AGING, 2020, 90 : 43 - 59
  • [10] From Subjective Cognitive Decline to Alzheimer's Disease: The Predictive Role of Neuropsychological Assessment, Personality Traits, and Cognitive Reserve. A 7-Year Follow-Up Study
    Bessi, Valentina
    Mazzeo, Salvatore
    Padiglioni, Sonia
    Piccini, Carolina
    Nacmias, Benedetta
    Sorbi, Sandro
    Bracco, Laura
    [J]. JOURNAL OF ALZHEIMERS DISEASE, 2018, 63 (04) : 1523 - 1535