Erenumab in a patient with persistent headaches after subarachnoid hemorrhage: A case report of an effective treatment

被引：0
|
作者：
Gandhi, Ajay [1 ]
Quinoa, Travis R. [1 ]
Geller, Eric [2 ]
Khandelwal, Priyank [1 ]
Agarwalla, Pankaj K. [1 ]
机构：
[1] Rutgers New Jersey Med Sch, Dept Neurol Surg, Newark, NJ 07103 USA
[2] Inst Neurol & Neursurg, Livingston, NJ USA
来源：
HEADACHE | 2025年 / 65卷 / 02期
关键词：
calcitonin gene-related peptide; erenumab; headache; migraine; subarachnoid hemorrhage; trigeminovascular system; GENE-RELATED PEPTIDE;
D O I：
10.1111/head.14884
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A patient with persistent refractory headaches from aneurysmal subarachnoid hemorrhage was treated with monthly erenumab injections, a monoclonal antibody to the calcitonin gene-related peptide (CGRP) receptor. These injections decreased the frequency and severity of the patient's debilitating headaches from daily to once or twice per month with positive improvement in function and quality of life. To our knowledge, this is the first reported case in the literature of a patient with persistent post-subarachnoid hemorrhage headache that was successfully treated with an antibody against the CGRP receptor. This case report highlights the role of CGRP in post-subarachnoid hemorrhage headaches and the potential role for CGRP pathway-based therapies as an effective treatment.
引用
收藏
页码：373 / 376
页数：4
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