Recent advancements in biomedical application of polylactic acid/graphene nanocomposites: An overview

被引：16

作者：

Adekoya, Gbolahan Joseph ^{[1
]}

Ezika, Anthony Chidi ^{[1
]}

Adekoya, Oluwasegun Chijioke ^{[1
]}

Sadiku, Emmanuel Rotimi ^{[1
]}

Hamam, Yskandar ^{[2
,3
]}

Ray, Suprakas Sinha ^{[4
,5
]}

机构：

[1] Tshwane Univ Technol, Inst Nanoengn Res INER, Fac Engn & Built Environm, Dept Chem Met & Mat Engn, Pretoria, South Africa

[2] Tshwane Univ Technol, French South African Inst Technol FSATI, Dept Elect Engn, Pretoria, South Africa

[3] Ecole Super Ingn Electrotech & Elect, Paris, France

[4] Council Sci & Ind Res CSIR, Ctr Nanostruct & Adv Mat, DSI CSIR Nanotechnol Innovat Ctr, ZA-0001 Pretoria, South Africa

[5] Univ Johannesburg, Dept Chem Sci, Johannesburg, South Africa

来源：

BMEMAT | 2023年 / 1卷 / 04期

基金：

新加坡国家研究基金会;

关键词：

biocompatibility; biodegradability; biomedical applications; fabrication techniques; PLA/graphene nanocomposites; GRAPHENE OXIDE; POLY(LACTIC ACID); THERMOMECHANICAL PROPERTIES; PLA; COMPOSITES; BIOCOMPATIBILITY; BIODEGRADATION; NANOPARTICLES; DELIVERY; BEHAVIOR;

D O I：

10.1002/bmm2.12042

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Polylactic acid (PLA)-graphene nanocomposites have attracted significant attention in the biomedical field because of their biodegradability, biocompatibility, and excellent mechanical properties. This review provides a comprehensive summary of the recent developments in the biomedical applications of PLA/graphene nanocomposites. The discussed applications include tissue engineering, drug delivery, biomedical imaging and sensing, antimicrobial and anticancer treatments, and photothermal and photodynamic therapies. The properties and synthesis of these nanocomposites are also addressed. This review shows that although significant advancements have been made in the development of biomedical applications for PLA/graphene nanocomposites, further research is still required to overcome the existing challenges and limitations, such as improving biocompatibility and biodegradability and optimizing synthesis and processing methods. Despite these challenges, the potential of PLA/graphene nanocomposites in the biomedical field is significant and holds promise for future advancements. Graphene-containing polylactic acid nanocomposites have gained significant attention in the biomedical field due to their biodegradability, biocompatibility, and excellent mechanical properties. This review reports the latest advancements in the biomedical use of PLA/graphene-based nanocomposites, focusing on drug delivery, biosensing, and tissue regeneration. image

引用

页数：23

共 117 条

[91] 3D-printed reduced graphene oxide/polylactic acid electrodes: A new prototyped platform for sensing and biosensing applications [J].