Emerging trends in early-onset gastric cancer

被引：0
作者：
Wang, Xinlin [1 ,2 ]
Gao, Xianchun [1 ,2 ]
Yu, Jun [1 ,2 ]
Zhang, Xiaotian [1 ,3 ]
Nie, Yongzhan [1 ,2 ]
机构：
[1] State Key Lab Holist Integrat Management Gastroint, Xian 710032, Shaanxi, Peoples R China
[2] Fourth Mil Med Univ, Xijing Hosp Digest Dis, Natl Clin Res Ctr Digest Dis, Xian 710032, Shaanxi, Peoples R China
[3] Peking Univ, Canc Hosp & Inst, Dept Gastrointestinal Oncol, Beijing Key Lab Carcinogenesis & Translat Res, Beijing 100142, Peoples R China
来源：
CHINESE MEDICAL JOURNAL | 2024年 / 137卷 / 18期
基金：
中国国家自然科学基金;
关键词：
Early-onset gastric cancer; Epidemiology; Etiology; Clinicopathological features; Molecular signaling; Prognosis; Clinical management; HELICOBACTER-PYLORI INFECTION; YOUNG-PATIENTS; AGE; SURVIVAL; EFFICACY; DIFFUSE; DISEASE;
D O I：
10.1097/CM9.0000000000003259
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The incidence of early-onset gastric cancer (EOGC) is consistently increasing, and its etiology is notably complex. This increase may be attributed to distinctive factors that differ from those associated with late-onset gastric cancer (LOGC), including genetic predispositions, dietary factors, gastric microbiota dysbiosis, and screening of high-risk cases. These factors collectively contribute to the onset of cancer. EOGC significantly differs from LOGC in terms of clinicopathological and molecular characteristics. Moreover, multiple differences in prognosis and clinical management also exist. This study aimed to systematically review the latest research advancements in the epidemiological characteristics, etiological factors, clinicopathological and molecular features, prognosis, and treatment modalities of EOGC.
引用
收藏
页码：2146 / 2156
页数：11
相关论文
共 50 条
[31]   Comprehensive characterization of early-onset lung cancer, in Chinese young adults [J].
Tian, Ye ;
Ma, Rui ;
Zhao, Wenchang ;
Wang, Shumin ;
Zhou, Chuanjiang ;
Wu, Weibing ;
Yang, Bo ;
Xin, Hua ;
Wang, Hongyan ;
Li, Pengfei ;
Li, Ranhua ;
Liu, Changhong ;
Lu, Yao ;
Yu, Qian ;
Song, Chengyang ;
Zhang, Han ;
Liang, Ruipu ;
Zhang, Lei ;
Zhou, Di ;
Zhao, Xitong ;
Wu, Zhuo ;
Qi, Yafei ;
Wang, Rui ;
Fei, Teng ;
Yang, Xueying .
NATURE COMMUNICATIONS, 2025, 16 (01)
[32]   Early-onset colorectal cancer: A separate subset of colorectal cancer [J].
Osorio Silla, Irene ;
Rueda, Daniel ;
Rodriguez, Yolanda ;
Luis Garcia, Juan ;
de la Cruz Vigo, Felipe ;
Perea, Jose .
WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (46) :17288-17296
[33]   Trends in Early-Onset Colorectal Cancer in Singapore: Epidemiological Study of a Multiethnic Population [J].
Chen, Hui Lionel Raphael ;
Chong, Qingqing Dawn ;
Tay, Brenda ;
Zhou, Siqin ;
Wong, Evelyn Yi Ting ;
Seow-En, Isaac ;
Tan, Ker Kan ;
Wang, Yi ;
Seow, Adeline ;
Tan, Kwong-Wei Emile ;
Tan, Bee Huat Iain ;
Tan, Sze Huey .
JMIR PUBLIC HEALTH AND SURVEILLANCE, 2025, 11
[34]   Comparing cohort and period trends of early-onset colorectal cancer: a global analysis [J].
Chen, Jianjiu ;
Yang, Wan .
JNCI CANCER SPECTRUM, 2024, 8 (04)
[35]   Proportion of Early-Onset Gastric and Esophagus Cancers Has Changed Over Time With Disproportionate Impact on Black and Hispanic Patients [J].
Torrejon, Nataly, V ;
Deshpande, Saarang ;
Wei, Wei ;
Tullio, Katherine ;
Kamath, Suneel D. .
JCO ONCOLOGY PRACTICE, 2022, 18 (05) :398-E769
[36]   Identification of New Genes Involved in Germline Predisposition to Early-Onset Gastric Cancer [J].
Herrera-Pariente, Cristina ;
Capo-Garcia, Roser ;
Diaz-Gay, Marcos ;
Carballal, Sabela ;
Munoz, Jenifer ;
Llach, Joan ;
Sanchez, Ariadna ;
Bonjoch, Laia ;
Arnau-Collell, Coral ;
Soares de Lima, Yasmin ;
Golubicki, Mariano ;
Jung, Gerhard ;
Lozano, Juan Jose ;
Castells, Antoni ;
Balaguer, Francesc ;
Bujanda, Luis ;
Castellvi-Bel, Sergi ;
Moreira, Leticia .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (03) :1-14
[37]   Early-onset colorectal cancer: A sporadic or inherited disease? [J].
Stigliano, Vittoria ;
Sanchez-Mete, Lupe ;
Martayan, Aline ;
Anti, Marcello .
WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (35) :12420-12430
[38]   Early-onset breast cancer - Histopathological and prognostic considerations [J].
Kollias, J ;
Elston, CW ;
Ellis, IO ;
Robertson, JFR ;
Blamey, RW .
BRITISH JOURNAL OF CANCER, 1997, 75 (09) :1318-1323
[39]   Early-onset colorectal cancer: A review of current knowledge [J].
Saraiva, Margarida R. ;
Rosa, Isadora ;
Claro, Isabel .
WORLD JOURNAL OF GASTROENTEROLOGY, 2023, 29 (08) :1289-1303
[40]   Early-Onset colorectal Cancer: From the laboratory to the clinic [J].
Gandini, Annalice ;
Taieb, Julien ;
Blons, Helene ;
Netter, Jeanne ;
Laurent-Puig, Pierre ;
Gallois, Claire .
CANCER TREATMENT REVIEWS, 2024, 130
12345