Pharmacological Inhibition of p38 MAPK Attenuates Doxorubicin-induced Cardiotoxicity, Senescence, and Inflammation in C57BL/6 mice

被引:0
|
作者
Dabour, Mohamed
Abdelgawad, Ibrahim
Sadaf, Bushra
Daniel, Mary Raphel
Grant, Marianne
Zordoky, Beshay
机构
关键词
D O I
10.1161/res.135.suppl_1.Mo002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Mo002
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibition of the p38 MAPK pathway in H9c2 cells
    Guo, Runmin
    Lin, Jiancong
    Xu, Wenming
    Shen, Ning
    Mo, Liqiu
    Zhang, Changran
    Feng, Jianqiang
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2013, 31 (03) : 644 - 650
  • [2] Vaccarin Ameliorates Doxorubicin-Induced Cardiotoxicity via Inhibition of p38 MAPK Mediated Mitochondrial Dysfunction
    Shi, Xin
    Cao, Yang
    Wang, Hongyu
    Zhao, Qi
    Yan, Cong
    Li, Shengzhu
    Jing, Ling
    JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 2024, 17 (05) : 1155 - 1171
  • [3] Xanthine oxidase inhibition attenuates doxorubicin-induced cardiotoxicity in mice
    Tanaka, Yoshiro
    Nagoshi, Tomohisa
    Yoshii, Akira
    Oi, Yuhei
    Takahashi, Hirotake
    Kimura, Haruka
    Ito, Keiichi
    Kashiwagi, Yusuke
    Tanaka, Toshikazu D.
    Yoshimura, Michihiro
    FREE RADICAL BIOLOGY AND MEDICINE, 2021, 162 : 298 - 308
  • [4] Xanthine oxidase inhibition attenuates doxorubicin-induced cardiotoxicity in mice
    Tanaka, Y.
    Nagoshi, T.
    Yoshii, A.
    Oi, Y.
    Takahashi, H.
    Kimura, H.
    Kashiwagi, Y.
    Tanaka, T. D.
    Yoshimura, M.
    EUROPEAN HEART JOURNAL, 2020, 41 : 3399 - 3399
  • [5] Comparing Flaxseed and Perindopril in the Prevention of Doxorubicin and Trastuzumab-Induced Cardiotoxicity in C57Bl/6 Mice
    Eekhoudt, Cameron R.
    Bortoluzzi, Tessa
    Varghese, Sonu S.
    Cheung, David Y. C.
    Christie, Simon
    Eastman, Skyler
    Mittal, Ishika
    Austria, J. Alejandro
    Aukema, Harold M.
    Ravandi, Amir
    Thliveris, James
    Singal, Pawan K.
    Jassal, Davinder S.
    CURRENT ONCOLOGY, 2022, 29 (05) : 2941 - 2953
  • [6] Sex-related differences in delayed doxorubicin-induced cardiac dysfunction in C57BL/6 mice
    Ibrahim Y. Abdelgawad
    Benu George
    Marianne K. O. Grant
    Yingbo Huang
    Yuting Shan
    R. Stephanie Huang
    Beshay N. Zordoky
    Archives of Toxicology, 2024, 98 : 1191 - 1208
  • [7] Sex-related differences in delayed doxorubicin-induced cardiac dysfunction in C57BL/6 mice
    Abdelgawad, Ibrahim Y.
    George, Benu
    Grant, Marianne K. O.
    Huang, Yingbo
    Shan, Yuting
    Huang, R. Stephanie
    Zordoky, Beshay N.
    ARCHIVES OF TOXICOLOGY, 2024, 98 (04) : 1191 - 1208
  • [8] Oridonin Alleviates Doxorubicin-Induced Cardiotoxicity by Inhibiting p38 MAPK/MMP3 Signaling Pathway
    Hou, Xingyuan
    Xie, Suifen
    Zhou, Ni
    Wei, Shanshan
    Yang, Yuanying
    Luo, Ziheng
    Liu, Sa
    Liu, Jian
    Xie, Ning
    Li, Wenqun
    Zhang, Bikui
    CHEMICAL BIOLOGY & DRUG DESIGN, 2025, 105 (03)
  • [9] CoQ10 Improves Myocardial Damage in Doxorubicin-Induced Heart Failure in C57BL/6 Mice
    Pei, Zuowei
    Ma, Liang
    Li, Yawen
    Yang, Jin
    Yang, Qin
    Yao, Wei
    Li, Shijun
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2022, 27 (08):
  • [10] p38 MAPK downregulates phosphorylation of Bad in doxorubicin-induced endothelial apoptosis
    Grethe, Simone
    Coltella, Nadia
    Di Renzo, Maria Flavia
    Porn-Ares, M. Isabella
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2006, 347 (03) : 781 - 790