IL-27: overclocking cytotoxic T lymphocytes to boost cancer immunotherapy

被引：0
作者：
Dusi, Silvia [1 ]
Bronte, Vincenzo [1 ]
De Sanctis, Francesco [2 ]
机构：
[1] IRCCS, Veneto Inst Oncol IOV, Padua, Italy
[2] Univ Verona, Dept Med, Sect Immunol, Verona, Italy
来源：
SIGNAL TRANSDUCTION AND TARGETED THERAPY | 2025年 / 10卷 / 01期
关键词：
D O I：
10.1038/s41392-025-02212-z
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页数：3
相关论文
共 5 条
[1]   IL-27 elicits a cytotoxic CD8+ T cell program to enforce tumour control [J].
Breart, Beatrice ;
Williams, Katherine ;
Krimm, Stellanie ;
Wong, Tiffany ;
Kayser, Brandon D. ;
Wang, Lifen ;
Cheng, Eric ;
Tleugabulova, Mayra Cruz ;
Bouziat, Romain ;
Lu, Tianshi ;
Yuen, Kobe ;
Firmino, Natalie S. ;
Bravo, Daniel D. ;
Roels, Juliette ;
Bhakta, Atish ;
Bevers, Jack ;
Lehoux, Isabelle ;
Gutierrez, Alan ;
Chestnut, Yajun ;
Klementowicz, Joanna E. ;
Arenzana, Teresita L. ;
Akhmetzyanova, Ilseyar ;
Dixon, Elizabeth ;
Chen, Min ;
Tasneem, Kazi ;
Yadav, Rajbharan ;
Koeppen, Hartmut ;
Oh, Soyoung A. ;
Delamarre, Lelia ;
Huang, Haochu ;
Lim, Shion A. ;
Nakamura, Gerald ;
Wang, Jianyong ;
Gao, Chan ;
Corpuz, Racquel ;
Mueller, Soeren ;
West, Nathaniel R. .
NATURE, 2025, 639 (8055) :746-753
[2]   Interleukin-27 Exerts Its Antitumor Effects by Promoting Differentiation of Hematopoietic Stem Cells to M1 Macrophages [J].
Chiba, Yukino ;
Mizoguchi, Izuru ;
Furusawa, Junichi ;
Hasegawa, Hideaki ;
Ohashi, Mio ;
Xu, Mingli ;
Owaki, Toshiyuki ;
Yoshimoto, Takayuki .
CANCER RESEARCH, 2018, 78 (01) :182-194
[3]   Targeting tumour-reprogrammed myeloid cells: the new battleground in cancer immunotherapy [J].
De Sanctis, Francesco ;
Adamo, Annalisa ;
Cane, Stefania ;
Ugel, Stefano .
SEMINARS IN IMMUNOPATHOLOGY, 2023, 45 (02) :163-186
[4]   The hallmarks of cancer immune evasion [J].
Galassi, Claudia ;
Chan, Timothy A. ;
Vitale, Ilio ;
Galluzzi, Lorenzo .
CANCER CELL, 2024, 42 (11) :1825-1863
[5]   Interleukin-27: Balancing Protective and Pathological Immunity [J].
Hunter, Christopher A. ;
Kastelein, Rob .
IMMUNITY, 2012, 37 (06) :960-969
1