Baicalin: an active natural product with potential medicinal values

被引:0
作者
Wen, Yong-Qiang [1 ]
Wang, Ya-Zhou [1 ]
Zhao, Chen-Xu [1 ]
Zhao, Bao-Yu [1 ]
Wang, Jian-Guo [1 ]
机构
[1] Northwest A&F Univ, Coll Vet Med, Yangling 712100, Peoples R China
基金
中国国家自然科学基金;
关键词
Baicalin; bioavailability; cytotoxicity; pharmacological properties; pharmacological function; NF-KAPPA-B; DIET-INDUCED OBESITY; OXIDATIVE STRESS; SCUTELLARIA-BAICALENSIS; SIGNALING PATHWAYS; COMPARATIVE PHARMACOKINETICS; COMBINATION THERAPY; TISSUE DISTRIBUTION; INSULIN-RESISTANCE; BIOACTIVE FLAVONES;
D O I
10.1080/10286020.2025.2482054
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Baicalin, a flavonoid derived from the dicotyledonous plant Scutellaria baicalensis Georgi (SBG), is applied to treat various disorders due to its various pharmacological effects such as anti-inflammatory, antiviral, antibacterial, liver-protecting, lipid-lowering, and neuroprotection. However, baicalin's limited solubility hampers absorption. This article reviews baicalin's pharmacological properties, including pharmacokinetics, cytotoxicity, drug interactions, and therapeutic potential, especially for cardiovascular diseases, obesity, and liver-lipid disorders, aiming to promote its development in medicine, dairy and livestock feed, nutritional health products and cosmetics for humans and other fields.
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页数:25
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