Long-Term Results and Quality of Life after Surgery for Acute Aortic Dissection Type A: Contemporary Single-Centre Experience

被引:0
作者
Goebel, Nora [1 ]
Holder, Simone A. [1 ]
Huether, Franziska [1 ]
Maw, Eleanor [2 ]
Ayala, Rafael [1 ]
Anguelov, Yasemin [3 ]
Franke, Ulrich F. W. [4 ]
Bail, Dorothee [1 ]
机构
[1] Robert Bosch Krankenhaus, Dept Cardiovasc Surg, D-70376 Stuttgart, Germany
[2] Univ Warwick, Warwick Med Sch, Coventry CV4 7AL, England
[3] Bosch Hlth Campus, Robert Bosch Soc Med Res, D-70376 Stuttgart, Germany
[4] Univ Heart Ctr Freiburg Bad Krozingen, Dept Cardiovasc Surg, D-79189 Bad Krozingen, Germany
关键词
type A aortic dissection; aortic surgery; long-term results; outcomes; reintervention; quality of life; FROZEN ELEPHANT TRUNK; INTERNATIONAL REGISTRY; OUTCOMES; HEALTH; TRENDS;
D O I
10.3390/jcm13185645
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Aortic dissection is still afflicted with significant morbidity and mortality. This research seeks to assess long-term outcomes and quality of life after emergency surgery for acute aortic dissection type A. Methods: A total of 413 patients were analysed, who had been operated upon between 2000 and 2016 at our centre. We compared our results of the early (2000-2007) versus late (2008-2016) period with regards to 30-day and follow-up mortality and need for reoperation, including risk factor analysis. Quality of life was assessed via the SF-36 survey. Results: Calculated perioperative risk by EuroSCORE increased significantly from early, 24.9%, to late, 38.0%, p < 0.001. Thirty-day rates of mortality decreased significantly from 26.7% to 17.4%, p = 0.03. Survival at 1-, 5-, and 10-years was 92.3% vs. 91.8% (p = 0.91), 75.2% vs. 81.0% (p = 0.29), and 53.4% vs. 69.7% (p = 0.04). Freedom from reoperation was comparable between groups at follow-up: 74.0% vs. 85.7%, p = 0.28. Quality of life was impaired. Conclusions: Despite more complex severity of disease and operative procedures, the results of surgery for type A aortic dissection improved significantly over time at 30-day and 10-year follow-up. Quality of life was significantly impaired compared to a healthy reference population.
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页数:12
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