Social Determinants of 6-Mercaptopurine Adherence Among Patients with Acute Lymphoblastic Leukemia/Lymphoma: A Cross-Sectional Analysis

被引:0
作者
El-khatib, Ayah [1 ,2 ]
Matos, Kevin [3 ]
Rossoff, Jenna [1 ,2 ]
Psihogios, Alexandra [2 ,3 ]
机构
[1] Ann & Robert H Lurie Childrens Hosp Chicago, Div Hematol Oncol & Stem Cell Transplant, 225 E Chicago Ave, Box 30, Chicago, IL 60611 USA
[2] Northwestern Univ, Feinberg Sch Med, Dept Pediat, Chicago, IL USA
[3] Northwestern Feinberg Sch Med, Dept Med Social Sci, Chicago, IL USA
基金
美国国家卫生研究院;
关键词
Social determinants; race/ethnicity; insurance; ADI; adherence; PEDIATRIC CANCER; 6MP ADHERENCE; LEUKEMIA; DISADVANTAGE; CHILDREN;
D O I
10.1089/jayao.2024.0119
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Acute lymphoblastic leukemia requires around 18 months of daily oral chemotherapy called 6-mercaptopurine (6-MP) for treatment. Previous research has included a broad age range and shows adolescent/young adult (AYA) age and minoritized race/ethnicity are associated with lower adherence. Few studies have evaluated how these intersecting identities impact adherence. In a retrospective analysis of an AYA sample, we evaluated the relationships between race/ethnicity, area deprivation index (ADI), and insurance with electronically monitored 6-MP adherence. Results showed minoritized race/ethnicity and ADI correlated with adherence. Findings highlight the need for equitable interventions that enhance adherence and improve outcomes among AYAs.
引用
收藏
页数:5
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