N-Heterocyclic Carbene Catalyzed Activation of Carboxylic Acids

被引：0
|
作者：
Qin, Yueling [1 ]
Li, Tingting [1 ]
机构：
[1] Guizhou Univ, State Key Lab Green Pesticide, Key Lab Green Pesticide & Agr Bioengn, Minist Educ, Guiyang 550025, Peoples R China
来源：
ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2025年 / 14卷 / 02期
关键词：
N-heterocyclic carbenes; Organocatalysis; Carboxylic acids; Activating agents; Reactive intermediates; IN-SITU ACTIVATION; ENANTIOSELECTIVE SYNTHESIS; COUPLING REAGENTS; CASCADE REACTION; LUMO ACTIVATION; 4+2 CYCLIZATION; ACCESS; ESTERS; CYCLOCONDENSATION; DIHYDROPYRANONES;
D O I：
10.1002/ajoc.202400585
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
N-heterocyclic carbene (NHC) catalyzed reactions of carboxylic acids play a crucial role in NHC catalysis, enabling the formation of chiral and achiral functional molecules. In this review, the achievements in NHC catalyzed activations of carboxylic acids are summarized, and an outlook on future research directions is also provided.
引用
收藏
页数：9
相关论文
共 50 条
  • [1] N-heterocyclic carbene-catalyzed atroposelective synthesis of N-Aryl phthalimides and maleimides via activation of carboxylic acids
    Barik, Soumen
    Ranganathappa, Sowmya Shree
    Biju, Akkattu T.
    NATURE COMMUNICATIONS, 2024, 15 (01)
  • [2] N-Heterocyclic carbene-catalyzed aerobic oxidation of aryl alkyl alcohols to carboxylic acids
    Yu, Dong-Fang
    Xing, Ping
    Jiang, Biao
    TETRAHEDRON, 2015, 71 (25) : 4269 - 4273
  • [3] An N-Heterocyclic Carbene-Catalyzed Oxidative γ-Aminoalkylation of Saturated Carboxylic Acids through in Situ Activation Strategy: Access to δ-Lactam
    Que, Yonglei
    Xie, Yuanwei
    Li, Tuanjie
    Yu, Chenxia
    Tu, Shujiang
    Yao, Changsheng
    ORGANIC LETTERS, 2015, 17 (24) : 6234 - 6237
  • [4] Reductive Synthesis of Alcohols from Carboxylic Acids and Esters Catalyzed by a Copper N-heterocyclic Carbene Complex
    Zhou, Hui
    Wei, Nana
    Ren, Zhiqiang
    Ma, Haojie
    Zhang, Yuqi
    Han, Bo
    CHINESE JOURNAL OF CHEMISTRY, 2025, 43 (01) : 73 - 78
  • [5] N-Heterocyclic Carbene Catalyzed Cyclocondensation of α,β-Unsaturated Carboxylic Acids: Enantioselective Synthesis of Pyrrolidinone and Dihydropyridinone Derivatives
    Chen, Xiang-Yu
    Gao, Zhong-Hua
    Song, Chun-Yu
    Zhang, Chun-Lin
    Wang, Zhi-Xiang
    Ye, Song
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (43) : 11611 - 11615
  • [6] N-Heterocyclic Carbene Catalyzed Transformylation
    Fernando, Jared E. M.
    Levens, Alison
    Moock, Daniel
    Lupton, David W.
    SYNTHESIS-STUTTGART, 2017, 49 (15): : 3505 - 3510
  • [7] Dehydrogenative Synthesis of Carboxylic Acids from Primary Alcohols and Hydroxide Catalyzed by a Ruthenium N-Heterocyclic Carbene Complex
    Santilli, Carola
    Makarov, Ilya S.
    Fristrup, Peter
    Madsen, Robert
    JOURNAL OF ORGANIC CHEMISTRY, 2016, 81 (20): : 9931 - 9938
  • [8] N-Heterocyclic Carbene Catalyzed Asymmetric Hydration: Direct Synthesis of α-Protio and α-Deuterio α-Chloro and α-Fluoro Carboxylic Acids
    Vora, Harit U.
    Rovis, Tomislav
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (09) : 2860 - +
  • [9] Enantioselective N-Heterocyclic Carbene Catalyzed α-Oxidative Coupling of Enals with Carboxylic Acids Using an Iodine(III) Reagent
    Xu, Yuan-Yuan
    Gao, Zhong-Hua
    Li, Cao-Bo
    Ye, Song
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 62 (11)
  • [10] β-Carbon activation of saturated carboxylic esters through N-heterocyclic carbene organocatalysis
    Zhenqian Fu
    Jianfeng Xu
    Tingshun Zhu
    Wendy Wen Yi Leong
    Yonggui Robin Chi
    Nature Chemistry, 2013, 5 : 835 - 839
12345