Left bundle branch pacing cardiac resynchronization therapy vs biventricular pacing cardiac resynchronization therapy-time to write a requiem for biventricular pacing-cardiac resynchronization therapy

被引：0
作者：
Pradhan, Akshyaya [1 ]
Saggu, Daljeet [2 ]
Bhandari, Monika [1 ]
机构：
[1] King Georges Med Univ, Dept Cardiol, Shahmina Rd, Lucknow 226003, Uttar Pradesh, India
[2] AIG Hosp, Dept Cardiac Electrophysiol, Hyderabad 500034, Telangana, India
来源：
WORLD JOURNAL OF CARDIOLOGY | 2025年 / 17卷 / 02期
关键词：
Heart failure; Left bundle branch block area pacing; Narrow QRS; New York Heart Association class; Left ventricular ejection fraction; COST-EFFECTIVENESS; HEART-FAILURE;
D O I：
10.4330/wjc.v17.i2.103356
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Cardiac resynchronization therapy (CRT) reduces heart failure (HF) hospitalizations and all-cause mortality in patients with HF with reduced ejection fraction with left bundle branch (LBB) block. Biventricular pacing (BVP) is considered the gold standard for achieving CRT; however, approximately 30%-40% of patients do not respond to BVP-CRT. Recent studies have demonstrated that LBB pacing (LBBP) produces remarkable results in CRT. In this meta-analysis, LBBP-CRT showed better outcomes than conventional BVP-CRT, including greater QRS duration reduction and left ventricular ejection fraction improvement, along with consistently lower pacing thresholds on follow-up. Additionally, there was a greater reduction in New York Heart Association class and brain natriuretic peptide levels. This study contributes to the growing body of encouraging data on LBBP-CRT from recent years. With ongoing technological advancements and increasing operator expertise, the day may not be far when LBBP-CRT becomes the standard of care rather than the exception.
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页数：8
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