Fabrication of polylactide composites with silver nanoparticles by sputtering deposition and their antimicrobial and antiviral applications

被引：1

作者：

Demchenko, Valeriy ^{[1
,2
]}

Mamunya, Yevgen ^{[1
,2
,3
]}

Sytnyk, Illia ^{[1
]}

Iurzhenko, Maksym ^{[1
,2
,3
]}

Krivtsun, Igor ^{[1
]}

Rybalchenko, Nataliya ^{[4
]}

Naumenko, Krystyna ^{[4
]}

Artiukh, Liubov ^{[4
]}

Kowalczuk, Marek ^{[2
,5
]}

Demchenko, Olena ^{[6
]}

Marynin, Andrii ^{[7
]}

机构：

[1] Natl Acad Sci Ukraine, EO Paton Elect Welding Inst, Kyiv, Ukraine

[2] Int Polish Ukrainian Res Lab ADPOLCOM, Zabrze, Poland

[3] Natl Acad Sci Ukraine, Inst Macromol Chem, Kyiv, Ukraine

[4] Natl Acad Sci Ukraine, Zabolotny Inst Microbiol & Virol, Kyiv, Ukraine

[5] Polish Acad Sci, Ctr Polymer & Carbon Mat, Zabrze, Poland

[6] Natl Acad Med Sci Ukraine, Natl Res Ctr Radiat Med, Kyiv, Ukraine

[7] Natl Univ Food Technol, Kyiv, Ukraine

来源：

POLYMER INTERNATIONAL | 2025年 / 74卷 / 03期

基金：

新加坡国家研究基金会;

关键词：

polylactide; sputtering deposition; silver-containing composites; properties; antimicrobial activity; antiviral activity; ALIPHATIC EPOXY-RESIN; POLY(L-LACTIC ACID); NANOCOMPOSITES; BEHAVIOR; MORPHOLOGY; BLENDS; GROWTH; FILMS; SALT;

D O I：

10.1002/pi.6707

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Silver-containing composites formed by sputtering deposition on the surface of polylactide (PLA) films have been developed; they contain a layer of silver nanoparticles of different thicknesses depending on the deposition time, namely 1, 3 and 5 min. It was found that with a deposition time of 5 min a layer with a thickness of ca 100 nm is formed. The average size of the Ag nanoparticles is 5.9 nm, and the average specific surface area Ssp is 97 m2 g-1. The samples obtained were characterized by wide-angle X-ray scattering, TEM, TGA and DSC and their antimicrobial, antiviral and cytotoxic properties were studied as well. It was found that the thinnest layer of silver (deposited for 1 min) has the greatest effect on the PLA's heat resistance and glass transition temperature. PLA-Ag composites formed by silver sputtering deposition show antimicrobial activity against the studied test cultures of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, and the activity of the samples increases with increasing duration of silver deposition. PLA-Ag composites formed by silver deposition for 5 min had a weak virucidal effect against herpes simplex virus type 1 and influenza virus type A. Irrespective of the sputtering time of silver the composites obtained were not cytotoxic; at a dilution of 1:10 and more they did not significantly inhibit the viability of MDCK, BHK and Hep-2 cells. (c) 2025 Society of Chemical Industry.

引用

页码：207 / 216

页数：10

共 59 条

[1] Growth of Silver Nanoparticles by DCMagnetron Sputtering [J].