Multisystem Inflammatory Syndrome in Children: A Comprehensive Review Over the Past Five Years

被引：0
作者：
Shyong, Olivia [1 ,2 ]
Alfakhri, Nora [1 ,2 ]
Bates, Sara V. [2 ,3 ]
Carroll, Ryan W. [1 ,2 ]
Gallagher, Krista [1 ]
Huang, Lena [4 ]
Madhavan, Vandana [2 ,5 ]
Murphy, Sarah A. [1 ,2 ]
Okrzesik, Sylvia A. [6 ]
Yager, Phoebe H. [1 ,2 ]
Yonker, Lael M. [2 ,7 ]
Lok, Josephine [1 ,2 ]
机构：
[1] Massachusetts Gen Hosp, Dept Pediat Pediat Crit Care Med, Boston, MA 02114 USA
[2] Harvard Med Sch, Boston, MA 02115 USA
[3] Massachusetts Gen Hosp, Dept Pediat Newborn Med, Boston, MA USA
[4] Touro Univ Nevada, Coll Osteopath Med, Henderson, NV USA
[5] Massachusetts Gen Hosp, Dept Pediat Pediat Infect Dis, Boston, MA USA
[6] Massachusetts Gen Hosp, Dept Pharm, Boston, MA USA
[7] Massachusetts Gen Hosp, Dept Pediat Pediat Pulm Med, Boston, MA USA
来源：
JOURNAL OF INTENSIVE CARE MEDICINE | 2025年
关键词：
COVID-19; MIS-C; Multisystem Inflammatory Syndrome; SARS-CoV2; inflammation; Neutrophils; IVIG; glucocorticoids; Cardiac; Immune dysregulation; pediatrics; critical care; intensive care unit; outcomes; CORONAVIRUS DISEASE 2019; ACUTE KIDNEY INJURY; SARS-COV-2; PIMS-TS; COVID-19; VACCINE; PEDIATRIC-PATIENTS; UNITED-STATES; MULTICENTER; RECOMMENDATIONS; ADOLESCENTS; INVOLVEMENT;
D O I：
10.1177/08850666251320558
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Multisystem Inflammatory Syndrome in Children: A Comprehensive Review over the Past Five Years This review explores many facets of Multisystem Inflammatory Syndrome in Children (MIS-C) over the previous 5 years. In the time since the COVID 19 pandemic gripped our medical systems, we can now explore the data that has been collected from the previous years. The literature has allowed us to better understand the impact of COVID 19 and the post illness occurrence of a severe systemic inflammatory disease on our youngest patient populations. This paper will outline the pathophysiology of MIS-C, the treatments utilized, short and long-term patient outcomes including epidemiological factors.
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页数：25
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