Signal switching electrochemical and fluorescence dual-mode sensing platform for carbendazim determination based on "two-in-one" magneto-fluorescent Cdots

被引：1

作者：

Jia, Yuzhen ^{[1
]}

Ke, Yuanmeng ^{[1
]}

Liu, Zhixiang ^{[1
]}

Yang, Huaixia ^{[1
]}

Miao, Mingsan ^{[1
,2
]}

Guo, Liang ^{[1
]}

机构：

[1] Henan Univ Chinese Med, Pharm Coll, Zhengzhou 450046, Peoples R China

[2] Collaborat Innovat Ctr Res & Dev Whole Ind Chain Y, Zhengzhou, Henan, Peoples R China

来源：

FOOD CHEMISTRY | 2025年 / 463卷

基金：

中国国家自然科学基金;

关键词：

Carbendazim; M; -CDs; Dual mode detection; Actual sample analysis; EFFICIENT;

D O I：

10.1016/j.foodchem.2024.141494

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An innovative method for carbendazim (CBZ) detection was developed, consisting of an electrochemical- fluorescence dual-mode biosensor based on magneto-fluorescent composite M-CDs. M-CDs, as the fluorescent probe of this sensor, could combine the electrical signal-ferrocene to achieve the "signal switching" by specifically recognizing CBZ through aptamers, of which magnetic property was used to quickly separate from complex substrates without interference. The dual-mode sensor based on M-CDs demonstrated excellent linear responses in both electrochemical and fluorescence assays. It achieved detection ranges of 10 fg/mL- 300 ng/mL and 60 fg/mL - 100 ng/mL with detection limits (LODs) of 1.4 fg/mL and 2.3 fg/mL. The sensor exhibited exceptional detection performance, stability and anti-interference. In addition, the results of the sensor in actual samples were consistent with those of enzyme-linked immunosorbent assay (ELISA), which further demonstrated that the sensor could accurately trace detecting CBZ in real samples and had a certain application prospect.

引用

页数：11