Radical-mediated chemo-divergent recyclization of 1,2,3,4-benzothiatriazine-1,1-dioxides: alkyl migration and dearomatization

被引：0
作者：
Nan, Jiang [1 ]
Yang, Shuai [1 ]
Huang, Guanjie [1 ]
Fan, Liangxin [2 ]
机构：
[1] Shaanxi Univ Sci & Technol, Coll Chem & Chem Engn, Key Lab Chem Addit China Natl Light Ind, Xian 710021, Peoples R China
[2] Henan Agr Univ, Coll Sci, Zhengzhou 450002, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2025年 / 61卷 / 29期
关键词：
ASYMMETRIC DEAROMATIZATION; ISOMERIZATION; CYCLIZATION;
D O I：
10.1039/d5cc00008d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A divergent denitrogenation/recyclization of 1,2,3,4-benzothiatriazine-1,1-dioxides is disclosed, including C(sp2)-alkyl transposition and aniline dearomatization. Regarding the alkyl migration process, a rare radical-mediated model is presented. Synthetically, sterically-congested biaryl sultams and ortho-all carbon quaternary stereocenter-substituted imines are expeditiously assembled in a simple reaction system. Mechanistic insights indicate that an innovative pattern of diradical-triggered addition probably plays an essential role in the process of C(sp2)-alkyl transformation.
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收藏
页码：5503 / 5506
页数：4
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