Recent Advances on the Synthesis and Application of α , α-Difluoro- β-aminophosphonates

被引：0
作者：
Du, Youlong [1 ]
Wang, Qian [1 ]
Mei, Haibo [1 ]
Pajkert, Romana [2 ]
Roeschenthaler, Gerd-Volker [2 ]
Han, Jianlin [1 ]
机构：
[1] Nanjing Forestry Univ, Coll Chem Engn, Jiangsu Coinnovat Ctr Efficient Proc & Utilizat Fo, Nanjing 210037, Peoples R China
[2] Constructor Univ Bremen gGmbH, Sch Sci, D-28759 Bremen, Germany
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 44卷 / 12期
基金：
中国国家自然科学基金;
关键词：
aminophosphonate; alpha; alpha-; difluoro-; f-aminophosphonate; carbene; diazo compound; amine; bioactive compound; CATALYTIC ASYMMETRIC-SYNTHESIS; DIAZO-COMPOUNDS; FLUORINATED AMINOPHOSPHONATES; STEREOSELECTIVE-SYNTHESIS; PHOSPHONIC-ACIDS; REAGENTS; AMINES; ALPHA; ALPHA-DIFLUORO-BETA-AMINOPHOSPHONATES; DIAZOALKANES; INHIBITORS;
D O I：
10.6023/cjoc202405013
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
alpha , alpha-Difluoro- f-aminophosphonates can be looked as structural analogies with alpha-amino acids, which have attracted great attention in biological and medicinal chemistry during the past decades. Furthermore, these compounds also belong to an important type of organic building blocks for the rapid synthesis of difluoromethylenephosphonate-containing molecules. Thus, the preparation and application of alpha , alpha-difluoro- f-aminophosphonates are hot research topics in organic phosphine chemistry. A comprehensive summary of the literature reports related to alpha , alpha-difluoro- f-aminophosphonates in recent years is presented. And aspects of synthesis and applications of alpha , alpha-difluoro- f-aminophosphonates are discussed, in order to provide critical guidance for the further development of reactions and applications for the synthesis of difluoromethylenephosphonate derivatives.
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收藏
页码：3686 / 3701
页数：16
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