Population Structure and Antimicrobial Resistance in Campylobacter jejuni and C. coli Isolated from Humans with Diarrhea and from Poultry, East Africa

被引：1

作者：

French, Nigel P. ^{[1
]}

Thomas, Kate M. ^{[2
]}

Amani, Nelson B. ^{[3
]}

Benschop, Jackie ^{[1
]}

Bigogo, Godfrey M. ^{[4
]}

Cleaveland, Sarah ^{[5
]}

Fayaz, Ahmed ^{[1
]}

Hugho, Ephrasia A. ^{[3
]}

Karimuribo, Esron D. ^{[6
]}

Kasagama, Elizabeth ^{[3
]}

Maganga, Ruth ^{[5
]}

Melubo, Matayo L. ^{[3
]}

Midwinter, Anne C. ^{[1
]}

Mmbaga, Blandina T. ^{[3
,7
]}

Mosha, Victor V. ^{[3
]}

Mshana, Fadhili I. ^{[3
]}

Munyua, Peninah ^{[8
]}

Ochieng, John B. ^{[4
]}

Rogers, Lynn ^{[1
]}

Sindiyo, Emmanuel ^{[9
]}

Swai, Emanuel S. ^{[10
]}

Verani, Jennifer R. ^{[8
]}

Widdowson, Marc-Alain ^{[8
]}

Wilkinson, David A. ^{[1
]}

Kazwala, Rudovick R. ^{[6
]}

Crump, John A. ^{[11
]}

Zadoks, Ruth N. ^{[5
,12
]}

机构：

[1] Massey Univ, Palmerston North, New Zealand

[2] Minist Primary Ind, Wellington, New Zealand

[3] Kilimanjaro Christian Med Ctr, Kilimanjaro Clin Res Inst, Moshi, Tanzania

[4] Kenya Med Res Inst KEMRI, Ctr Global Hlth Res, Kisumu, Kenya

[5] Univ Strathclyde, Glasgow, Scotland

[6] Sokoine Univ Agr, Morogoro, Tanzania

[7] Kilimanjaro Christian Med Univ Coll, Moshi, Tanzania

[8] US Ctr Dis Control & Prevent, Nairobi, Kenya

[9] Nelson Mandela African Inst Sci & Technol, Arusha, Tanzania

[10] Minist Livestock & Fisheries, Dodoma, Tanzania

[11] Univ Otago, Dunedin, New Zealand

[12] Univ Sydney, Sydney, NSW, Australia

来源：

EMERGING INFECTIOUS DISEASES | 2024年 / 30卷 / 10期

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会; 英国经济与社会研究理事会; 英国自然环境研究理事会;

关键词：

THERMOPHILIC CAMPYLOBACTER; MOROGORO MUNICIPALITY; QUINOLONE RESISTANCE; PCR ASSAY; IDENTIFICATION; EPIDEMIOLOGY; INFECTIONS; PREVALENCE; MECHANISM; CHILDREN;

D O I：

10.3201/eid3010.231399

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Campylobacteriosis and antimicrobial resistance (AMR) are global public health concerns. Africa is estimated to have the world's highest incidence of campylobacteriosis and a relatively high prevalence ofAMR in Campylobacterspp. from humans and animals. Few studies have compared Campylobacter spp. isolated from humans and poultry in Africa using whole-genome sequencing and antimicrobial susceptibility testing. We explored the population structure and AMR of 178 Campylobacter isolates from East Africa, 81 from patients with diarrhea in Kenya and 97 from 56 poultry samples in Tanzania, collected during 2006-2017. Sequence type diversity was high in both poultry and human isolates, with some sequence types in common. The estimated prevalence of multidrug resistance, defined as resistance to >3 antimicrobial classes, was higher in poultry isolates (40.9%, 95% credible interval 23.6%-59.4%) than in human isolates (2.5%, 95% credible interval 0.3%-6.8%), underlining the importance of antimicrobial stewardship in livestock systems.

引用

页码：2079 / 2089

页数：11

共 50 条

[31] Multilocus sequence typing of Campylobacter jejuni and Campylobacter coli isolates from poultry, cattle and humans in Nigeria
Ngulukun, S.
Oboegbulem, S.
Klein, G.
JOURNAL OF APPLIED MICROBIOLOGY, 2016, 121 (02) : 561 - 568
[32] Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas
Bernadeta Szczepanska
Małgorzata Andrzejewska
Dorota Spica
Jacek J. Klawe
BMC Microbiology, 17
[33] Sharing of cmeRABC alleles between C. coli and C. jejuni associated with extensive drug resistance in Campylobacter isolates from infants and poultry in the Peruvian Amazon
Cooper, Kerry K.
Mourkas, Evangelos
Schiaffino, Francesca
Parker, Craig T.
Vasquez, Tackeshy N. Pinedo
Bardales, Paul F. Garcia
Yori, Pablo Penataro
Olortegui, Maribel Paredes
Villanueva, Katia Manzanares
Cachique, Lucero Romaina
Delgado, Hermann Silva
Hitchings, Matthew D.
Huynh, Steven
Sheppard, Samuel K.
Pascoe, Ben
Kosek, Margaret N.
MBIO, 2025, 16 (02)
[34] Multilocus Sequence Types and Antimicrobial Resistance of Campylobacter jejuni and C. coli Isolates of Human Patients From Beijing, China, 2017-2018
Zhang, Penghang
Zhang, Xiaoai
Liu, Yuzhu
Jiang, Jinru
Shen, Zhangqi
Chen, Qian
Ma, Xiaochen
FRONTIERS IN MICROBIOLOGY, 2020, 11
[35] Quadruplex qPCR for detection and discrimination of C. Coli,C. fetus, and C. Jejuni from other Campylobacter species in chicken and sheep meat
Abu-Halaweh, Marwan
Al-bsoul, Eman
BRAZILIAN JOURNAL OF MICROBIOLOGY, 2024, 55 (03) : 2547 - 2556
[36] Antimicrobial Resistance in Campylobacter coli and Campylobacter jejuni from Human Campylobacteriosis in Taiwan, 2016 to 2019
Liao, Ying-Shu
Chen, Bo-Han
Teng, Ru-Hsiou
Wang, You-Wun
Chang, Jui-Hsien
Liang, Shiu-Yun
Tsao, Chi-Sen
Hong, Yu-Ping
Sung, Hui-Yung
Chiou, Chien-Shun
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2022, 66 (01)
[37] Distribution of Colonization and Antimicrobial Resistance Genes in Campylobacter jejuni Isolated from Chicken
Thibodeau, Alexandre
Fravalo, Philippe
Garneau, Philippe
Masson, Luke
Laurent-Lewandowski, Sylvette
Quessy, Sylvain
Harel, Josee
Letellier, Ann
FOODBORNE PATHOGENS AND DISEASE, 2013, 10 (04) : 382 - 391
[38] Comparison of Campylobacter jejuni pulsotypes isolated from humans and poultry in Split and Dalmatia County, Croatia
Kovacic, Ana
Carev, Merica
Tripkovic, Ingrid
Srecec, Sinisa
Sisko-Kraljevic, Katarina
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH, 2015, 25 (01) : 10 - 20
[39] Multilocus Sequence Typing and Antimicrobial Resistance of Campylobacter jejuni Isolated from Dairy Calves in Austria
Klein-Joebstl, Daniela
Sofka, Dmitri
Iwersen, Michael
Drillich, Marc
Hilbert, Friederike
FRONTIERS IN MICROBIOLOGY, 2016, 7
[40] Antimicrobial resistance and interspecies gene transfer in Campylobacter coli and Campylobacter jejuni isolated from food animals, poultry processing, and retail meat in North Carolina, 2018-2019
Hull, Dawn M.
Harrell, Erin
van Vliet, Arnoud H. M.
Correa, Maria
Thakur, Siddhartha
PLOS ONE, 2021, 16 (02):

← 1 2 3 4 5 →