Comparison of outcomes of laparotomic and minimally invasive radical hysterectomy in women with early-stage cervical cancer

被引:1
|
作者
Chang, Shu-Han [1 ,2 ,3 ]
Huang, Kuan-Gen [1 ,2 ,3 ,4 ]
Yang, Lan-Yan [5 ]
Pan, Yu-Bin [6 ]
Lai, Chyong-Huey [1 ,2 ,3 ,4 ]
Chou, Hung-Hsueh [1 ,2 ,3 ,7 ]
机构
[1] Chang Gung Mem Hosp, Dept Obstet & Gynecol, Linkou Branch, 5 Fu Shin St, Taoyuan 333, Taiwan
[2] Chang Gung Univ, 5 Fu Shin St, Taoyuan 333, Taiwan
[3] Chang Gung Mem Hosp, Gynecol Canc Res Ctr, Linkou Branch, Taoyuan, Taiwan
[4] Chang Gung Univ, Coll Med, Taoyuan, Taiwan
[5] Taichung Vet Gen Hosp, Dept Med Res, Div Clin Trial, Taichung, Taiwan
[6] Linkou Chang Gung Mem Hosp, Clin Trial Ctr, Taoyuan, Taiwan
[7] Natl Tsing Hua Univ, Sch Med, Hsinchu, Taiwan
关键词
Cervical Cancer; Hysterectomy; Laparoscopy; Laparotomy; Minimally Invasive Surgical Procedures; SURVIVAL; SURGERY; RECURRENCE; EXPERIENCE;
D O I
10.3802/jgo.2024.35.e60
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objective: This study compared the outcomes of laparotomic radical hysterectomy (LRH) and minimally invasive radical hysterectomy (MISRH) in patients with early-stage cervical cancer. Methods: The clinical data of patients with early-stage cervical cancer who underwent LRH or MISRH (laparoscopic/robotic) at Chang Gung Memorial Hospital, Linkou Branch, from 2002 to 2017 were retrospectively reviewed. The surgical safety (operation time, blood loss, blood transfusion rate, length ofpostoperative stay, and perioperative complications), overall survival (OS), disease-free survival (DFS), and recurrence pattern were analyzed. Propensity score matching (PSM) at a 3:1 ratio was performed to balance prognostic variables. Results: Of the 760 patients (entire cohort), 614 underwent LRH and 146 underwent MISRH. After PSM, 394 and 140 patients were included in the LRH and MISRH groups, respectively. The 5-year OS rate was significantly lower in the MISRH group than in the LRH group (85.6% vs. 93.2%, p=0.043), and the 5-year DFS rate (p=0.21) did not differ significantly. After PSM, the 5-year OS rates did not differ significantly between the MISRH and LRH groups (87.1% vs. 92.1%, p=0.393). The MISRH group had a significantly shorter operation time (p<0.001), lower intraoperative blood loss (p<0.001), lower blood transfusion rate (p<0.001), and shorter postoperative stay (p<0.001) but a significantly higher rate of intraoperative bladder injury (p<0.001) than the LRH group. Conclusion: After PSM, MISRH is associated with nonsignificantly lower OS but a significantly higher risk of intraoperative urological complications than LRH.
引用
收藏
页数:12
相关论文
共 50 条
  • [31] ONCOLOGICAL OUTCOMES OF MINIMALLY INVASIVE RADICAL HYSTERECTOMY VERSUS RADICAL ABDOMINAL HYSTERECTOMY IN PATIENTS WITH EARLY STAGE CERVICAL CANCER: A MULTICENTER RETROSPECTIVE ANALYSIS
    Rodriguez, J.
    Hain, J. Rauh
    Saenz, J.
    Isla, D.
    Rendon, G.
    Odetto, D.
    Martinelli, F.
    Villoslada, V.
    Zapardiel, I.
    Trujillo, L.
    Perez, M.
    Hernandez, M.
    Saadi, J.
    Raspagliesi, F.
    Valdivia, H. V.
    Siegrist, J.
    Fu, S.
    Hernandez, M.
    Echeverry, L.
    Noll, F.
    Ditto, A.
    Lopez, A.
    Hernandez, A.
    Pareja, R.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2020, 30 : A87 - A87
  • [32] Assessing the role of minimally invasive radical hysterectomy for early-stage cervical cancer (vol 275, pg 64, 2022)
    Bogani, Giorgio
    Di Donato, Violante
    Muzii, Ludovico
    Casarin, Jvan
    Ghezzi, Fabio
    Malzoni, Mario
    Greggi, Stefano
    Landoni, Fabio
    Bazzurini, Luca
    Zanagnolo, Vanna
    Multinu, Francesco
    Angioli, Roberto
    Plotti, Francesco
    Caruso, Giuseppe
    Fischetti, Margherita
    Ferrandina, Gabriella
    Palaia, Innocenza
    Panici, Pierluigi Benedetti
    Scambia, Giovanni
    Raspagliesi, Francesco
    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2022, 278 : 66 - 66
  • [33] The MEMORY Study: MulticentEr study of Minimally invasive surgery versus Open Radical hYsterectomy in the management of early-stage cervical cancer: Survival outcomes
    Leitao, Mario M.
    Zhou, Qin C.
    Brandt, Benny
    Iasonos, Alexia
    Sioulas, Vasileios
    Mager, Katherine Lavigne
    Shahin, Mark
    Bruce, Shaina
    Black, Destin R.
    Kay, Carrie G.
    Gandhi, Meeli
    Qayyum, Maira
    Scalici, Jennifer
    Jones, Nathaniel L.
    Paladugu, Rajesh
    Brown, Jubilee
    Naumann, R. Wendel
    Levine, Monica D.
    Mendivil, Alberto
    Lim, Peter C.
    Kang, Elizabeth
    Cantrell, Leigh A.
    Sullivan, Mackenzie W.
    Martino, Martin A.
    Kratz, Melissa K.
    Kolev, Valentin
    Tomita, Shannon
    Leath III, Charles A.
    Boitano, Teresa K. L.
    Doo, David W.
    Feltmate, Colleen
    Sugrue, Ronan
    Olawaiye, Alexander B.
    Goldfeld, Ester
    Ferguson, Sarah E.
    Suhner, Jessa
    Abu-Rustum, Nadeem R.
    GYNECOLOGIC ONCOLOGY, 2022, 166 (03) : 417 - 424
  • [34] Laparotomic radical hysterectomy versus minimally invasive radical hysterectomy using vaginal colpotomy for the management of stage IB1 to IIA2 cervical cancer Survival outcomes
    Yang, Eun Jung
    Kim, Nae Ry
    Lee, A. Jin
    Shim, Seung-Hyuk
    Lee, Sun Joo
    MEDICINE, 2022, 101 (08) : E28911
  • [35] Minimally-invasive hysterectomy versus open radical hysterectomy in early-stage cervical cancer: a cost-effective analysis of the LACC trial
    Boitano, Teresa
    Dilley, Sarah
    Smith, Haller
    Leath, Charles
    Straughn, Michael
    GYNECOLOGIC ONCOLOGY, 2021, 162 : S36 - S36
  • [36] Systematic comparison of radical vaginal trachelectomy and radical hysterectomy in the treatment of early-stage cervical cancer
    Han, Ling
    Yang, Xiao-Yun
    Zheng, Ai
    Wang, Li
    Chu, Yan-Xia
    Wang, Yu
    INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2011, 112 (02) : 149 - 153
  • [37] Outcomes of Minimally Invasive versus Open Radical Hysterectomy for Early Stage Cervical Cancer Incorporating 2018 FIGO Staging
    Levine, Monica D.
    Brown, Jubilee
    Crane, Erin K.
    Tait, David L.
    Naumann, R. Wendel
    JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY, 2021, 28 (04) : 824 - 828
  • [38] Does the association between minimally invasive hysterectomy and all-cause mortality differ between women undergoing simple or radical hysterectomy for early-stage cervical cancer?
    Sia, T. Y.
    St Clair, C. M.
    Hou, J. Y.
    Tergas, A. I.
    Collado, F. Khoury
    Wright, J. D.
    Melamed, A.
    GYNECOLOGIC ONCOLOGY, 2020, 159 : 191 - 191
  • [39] Sexual dysfunction in Thai women with early-stage cervical cancer after radical hysterectomy
    Tangjitgamol, S.
    Manusirivithaya, S.
    Hanprasertpong, J.
    Kasemsarn, P.
    Soonthornthum, T.
    Leelahakorn, S.
    Thawaramara, T.
    Lapcharoen, O.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2007, 17 (05) : 1104 - 1112
  • [40] Laparoscopic Compared With Open Radical Hysterectomy in Obese Women With Early-Stage Cervical Cancer
    Park, Jeong-Yeol
    Kim, Dae-Yeon
    Kim, Jong-Hyeok
    Kim, Yong-Man
    Kim, Young-Tak
    Nam, Joo-Hyun
    OBSTETRICS AND GYNECOLOGY, 2012, 119 (06): : 1201 - 1209