Ir(III)-catalyzed C-H alkenylation/annulation of N-iminopyridinium ylides with acrylates and alkynes

被引：0
作者：
Chen, Xiaopei [1 ]
Ma, Zhiwei [1 ]
Wang, Chuanchuan [1 ]
Hou, Xuehui [1 ]
Liu, Juntao [1 ]
机构：
[1] Henan Univ Anim Husb & Econ, Fac Sci, 2 Yingcai St, Zhengzhou 450044, Henan, Peoples R China
来源：
TETRAHEDRON | 2024年 / 168卷
关键词：
Ir(III) catalysis; C-H bond activation; Alkenylation; Annulation; Oxidant free; N-Iminopyridinium ylides; BOND FORMATION; ISOQUINOLONE SYNTHESIS; INTERNAL OXIDANT; O BOND; ACTIVATION; CYCLIZATION; OLEFINATION; ARYLATION; CARBON; ROUTE;
D O I：
10.1016/j.tet.2024.134322
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile and efficient protocol for Ir(III)-catalyzed ortho-alkenylation and annulation of N-iminopyridinium ylides with acrylates and alkynes has been developed, providing o-alkenyl benzamides and isoquinolones in good to excellent yields. This reaction proceeds well under external oxidant free conditions with high practicality and efficiency, and broad functional group tolerance.
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页数：10
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