Ir(III)-catalyzed C-H alkenylation/annulation of N-iminopyridinium ylides with acrylates and alkynes

被引：0

作者：

Chen, Xiaopei ^{[1
]}

Ma, Zhiwei ^{[1
]}

Wang, Chuanchuan ^{[1
]}

Hou, Xuehui ^{[1
]}

Liu, Juntao ^{[1
]}

机构：

[1] Henan Univ Anim Husb & Econ, Fac Sci, 2 Yingcai St, Zhengzhou 450044, Henan, Peoples R China

来源：

TETRAHEDRON | 2024年 / 168卷

关键词：

Ir(III) catalysis; C-H bond activation; Alkenylation; Annulation; Oxidant free; N-Iminopyridinium ylides; BOND FORMATION; ISOQUINOLONE SYNTHESIS; INTERNAL OXIDANT; O BOND; ACTIVATION; CYCLIZATION; OLEFINATION; ARYLATION; CARBON; ROUTE;

D O I：

10.1016/j.tet.2024.134322

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile and efficient protocol for Ir(III)-catalyzed ortho-alkenylation and annulation of N-iminopyridinium ylides with acrylates and alkynes has been developed, providing o-alkenyl benzamides and isoquinolones in good to excellent yields. This reaction proceeds well under external oxidant free conditions with high practicality and efficiency, and broad functional group tolerance.

引用

页数：10

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