Reductive Desulfonylation of Sulfonamides under Polysulfide Anions Photocatalysis

被引：0
|
作者：
Feng, Zixuan [1 ]
Tan, Eugene Yew Kun [1 ]
Chiba, Shunsuke [1 ]
机构：
[1] Nanyang Technol Univ, Sch Chem Chem Engn & Biotechnol, Singapore 637371, Singapore
来源：
ORGANIC LETTERS | 2025年
关键词：
ELECTRON-TRANSFER; PROTECTING GROUP; DEPROTECTION; CLEAVAGE; AMINES; MILD; ARENESULFONAMIDES; NITROGEN; ESTERS; AMIDES;
D O I：
10.1021/acs.orglett.5c01013
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We demonstrate that polysulfide anions are capable of catalyzing desulfonylation of sulfonamides having a series of aryl and alkyl substituents in the presence of potassium formate under irradiation with visible light. The developed protocol is operationally concise and cost-effective, representing a practical and sustainable synthetic tool for desulfonylation and expanding the chemical space in secondary amine synthesis.
引用
收藏
页码：4026 / 4031
页数：6
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